RIPK3 (Human) Recombinant Protein (Q01)
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Specification
Product Description
Human RIPK3 partial ORF ( AAH62584, 418 a.a. - 518 a.a.) recombinant protein with GST-tag at N-terminal.
Sequence
SPGPRGNQGAERQGMNWSCRTPEPNPVTGRPLVNIYNCSGVQVGDNNYLTMQQTTALPTWGLAPSGKGRGLQHPPPVGSQEGPKDPEAWSRPQGWYNHSGK
Host
Wheat Germ (in vitro)
Theoretical MW (kDa)
36.74
Interspecies Antigen Sequence
Mouse (59); Rat (60)
Preparation Method
Purification
Glutathione Sepharose 4 Fast Flow
Quality Control Testing
12.5% SDS-PAGE Stained with Coomassie Blue.
Storage Buffer
50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.
Storage Instruction
Store at -80°C. Aliquot to avoid repeated freezing and thawing.
Note
Best use within three months from the date of receipt of this protein.
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Applications
Enzyme-linked Immunoabsorbent Assay
Western Blot (Recombinant protein)
Antibody Production
Protein Array
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Gene Info — RIPK3
Entrez GeneID
11035GeneBank Accession#
BC062584Protein Accession#
AAH62584Gene Name
RIPK3
Gene Alias
RIP3
Gene Description
receptor-interacting serine-threonine kinase 3
Omim ID
605817Gene Ontology
HyperlinkGene Summary
The product of this gene is a member of the receptor-interacting protein (RIP) family of serine/threonine protein kinases, and contains a C-terminal domain unique from other RIP family members. The encoded protein is predominantly localized to the cytoplasm, and can undergo nucleocytoplasmic shuttling dependent on novel nuclear localization and export signals. It is a component of the tumor necrosis factor (TNF) receptor-I signaling complex, and can induce apoptosis and weakly activate the NF-kappaB transcription factor. [provided by RefSeq
Other Designations
RIP-like protein kinase 3|receptor interacting protein 3
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Interactome
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Disease
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