STIP1 (Human) IP-WB Antibody Pair
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More Files
- More Functions
Immunoprecipitation of STIP1 transfected lysate using mouse monoclonal anti-STIP1 and Protein A Magnetic Bead (U0007), and immunoblotted with rabbit polyclonal anti-STIP1.
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Specification
Product Description
This IP-WB antibody pair set comes with one antibody for immunoprecipitation and another to detect the precipitated protein in western blot.
Reactivity
Human
Interspecies Antigen Sequence
Mouse (97); Rat (97)
Quality Control Testing
Immunoprecipitation-Western Blot (IP-WB)
Immunoprecipitation of STIP1 transfected lysate using mouse monoclonal anti-STIP1 and Protein A Magnetic Bead (U0007), and immunoblotted with rabbit polyclonal anti-STIP1.
Supplied Product
Antibody pair set content:
1. Antibody pair for IP: mouse monoclonal anti-STIP1 (300 ug)
2. Antibody pair for WB: rabbit polyclonal anti-STIP1 (50 ul)
Storage Instruction
Store reagents of the antibody pair set at -20°C or lower. Please aliquot to avoid repeated freeze thaw cycle. Reagents should be returned to -20°C storage immediately after use.
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Applications
Immunoprecipitation-Western Blot
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Gene Info — STIP1
Entrez GeneID
10963Gene Name
STIP1
Gene Alias
HOP, IEF-SSP-3521, P60, STI1, STI1L
Gene Description
stress-induced-phosphoprotein 1
Omim ID
605063Gene Ontology
HyperlinkGene Summary
STIP1 is an adaptor protein that coordinates the functions of HSP70 (see HSPA1A; MIM 140550) and HSP90 (see HSP90AA1; MIM 140571) in protein folding. It is thought to assist in the transfer of proteins from HSP70 to HSP90 by binding both HSP90 and substrate-bound HSP70. STIP1 also stimulates the ATPase activity of HSP70 and inhibits the ATPase activity of HSP90, suggesting that it regulates both the conformations and ATPase cycles of these chaperones (Song and Masison, 2005 [PubMed 16100115]).[supplied by OMIM
Other Designations
Hsp70/Hsp90-organizing protein|stress-induced-phosphoprotein 1 (Hsp70/Hsp90-organizing protein)
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Interactome
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Pathway
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Disease
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