MLLT11 DNAxPab
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Specification
Product Description
Rabbit polyclonal antibody raised against a full-length human MLLT11 DNA using DNAx™ Immune technology.
Technology
Immunogen
Full-length human DNA
Sequence
MRDPVSSQYSSFLFWRMPIPELDLSELEGLGLSDTATYKVKDSSVGKMIGQATAADQEKNPEGDGLLEYSTFNFWRAPIASIHSFELDLL
Host
Rabbit
Reactivity
Human
Purification
Protein A
Quality Control Testing
Antibody reactive against mammalian transfected lysate.
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Transfected lysate)
Immunofluorescence (Transfected cell)
Flow Cytometry (Transfected cell)
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Gene Info — MLLT11
Entrez GeneID
10962GeneBank Accession#
NM_006818.3Protein Accession#
NP_006809.1Gene Name
MLLT11
Gene Alias
AF1Q, RP11-316M1.10
Gene Description
myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 11
Omim ID
604684Gene Ontology
HyperlinkGene Summary
The gene variously symbolized ALL1, HRX, or MLL located on 11q23 has been demonstrated to be fused with a number of translocation partners in cases of leukemia. t(1;11)(q21;q23) translocations that fused the MLL gene to a gene on chromosomal band 1q21 in 2 infants with acute myelomonocytic leukemia have been demonstrated. The N-terminal portion of the MLL gene is critical for leukemogenesis in translocations involving band 11q23. This gene encodes 90 amino acids. It was found to be highly expressed in the thymus but not in peripheral lymphoid tissues. In contrast to its restricted distribution in normal hematopoietic tissue, this gene was expressed in all leukemic cell lines tested. [provided by RefSeq
Other Designations
ALL1 fused gene from chromosome 1q|ALL1-fused gene from chromosome 1q|MLLT11 protein|OTTHUMP00000033120
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