PDE10A monoclonal antibody (M02), clone 4E1
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More Files
- More Functions
Sandwich ELISA (Recombinant protein)
Detection limit for recombinant GST tagged PDE10A is approximately 0.03ng/ml as a capture antibody.
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Specification
Product Description
Mouse monoclonal antibody raised against a partial recombinant PDE10A.
Immunogen
PDE10A (NP_006652, 242 a.a. ~ 333 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Sequence
GLAKQTELNDFLLDVSKTYFDNIVAIDSLLEHIMIYAKNLVNADRCALFQVDHKNKELYSDLFDIGEEKEGKPVFKKTKEIRFSIEKGIAGQ
Host
Mouse
Reactivity
Human
Interspecies Antigen Sequence
Mouse (98); Rat (100)
Isotype
IgG1 Kappa
Quality Control Testing
Antibody Reactive Against Recombinant Protein.
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Sandwich ELISA (Recombinant protein)
Detection limit for recombinant GST tagged PDE10A is approximately 0.03ng/ml as a capture antibody.ELISA
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Gene Info — PDE10A
Entrez GeneID
10846GeneBank Accession#
NM_006661Protein Accession#
NP_006652Gene Name
PDE10A
Gene Alias
FLJ11894, FLJ25677, HSPDE10A
Gene Description
phosphodiesterase 10A
Omim ID
610652Gene Ontology
HyperlinkGene Summary
Various cellular responses are regulated by the second messengers cAMP and cGMP. Phosphodiesterases, such as PDE10A, eliminate cAMP- and cGMP-mediated intracellular signaling by hydrolyzing the cyclic nucleotide to the corresponding nucleoside 5-prime monophosphate (Fujishige et al., 2000 [PubMed 10998054]).[supplied by OMIM
Other Designations
OTTHUMP00000017586|dJ416F21.1 (phosphodiesterase 10A)|phosphodiesterase 10A1 (PDE10A1)
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Pathway
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Disease
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