NOXA1 rabbit monoclonal antibody
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Specification
Product Description
Rabbit monoclonal antibody raised against a human NOXA1 peptide using ARM Technology.
Immunogen
A synthetic peptide of human NOXA1 is used for rabbit immunization.
Customer or Abnova will decide on the preferred peptide sequence.Host
Rabbit
Library Construction
Non-fusion antibody library from rabbit spleen (ARM Technology).
Expression
Overexpression vector and transfection into 293H cell line.
Reactivity
Human
Purification
Protein A
Isotype
IgG
Quality Control Testing
Antibody reactive against human NOXA1 peptide by ELISA and mammalian transfected lysate by Western Blot.
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
Deliverable
Up to three rabbit IgG clones of 100 ug each will be delivered to customer.
Note
1. Customer may provide cell or tissue lysate for antibody screening.
2. Rabbit monoclonal antibody generated by ARM technology is amenable to antibody engineering including F(ab)2, IgG, scFv and different Fc and non-Fc conjugates per customer request. -
Applications
Western Blot (Transfected lysate)
ELISA
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Gene Info — NOXA1
Entrez GeneID
10811GeneBank Accession#
NOXA1Gene Name
NOXA1
Gene Alias
FLJ25475, MGC131800, NY-CO-31, SDCCAG31, p51NOX
Gene Description
NADPH oxidase activator 1
Omim ID
611255Gene Ontology
HyperlinkGene Summary
NADPH oxidases (NOXs) catalyze the transfer of electrons from NADPH to molecular oxygen to generate reactive oxygen species (ROS). The NOX activator NOXA1 can stimulate both NOX1 (MIM 300225) and NOX2 (CYBB; MIM 300481), but it appears to be more effective in activating NOX1 (Opitz et al., 2007 [PubMed 17189823]).[supplied by OMIM
Other Designations
Nox activator 1|inhibitory NADPH oxidase activator 1|p67phox-like factor|serologically defined colon cancer antigen 31
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Interactome
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