CTCF polyclonal antibody (A01)
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More Files
- More Functions
Western Blot (Cell lysate)
CTCF polyclonal antibody (A01), Lot # 050727JC01 Western Blot analysis of CTCF expression in HL-60 ( Cat # L014V1 ).
Western Blot detection against Immunogen (37 KDa) .
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Specification
Product Description
Mouse polyclonal antibody raised against a partial recombinant CTCF.
Immunogen
CTCF (AAH14267, 1 a.a. ~ 100 a.a) partial recombinant protein with GST tag.
Sequence
MEGDAVEAIVEESETFIKGKERKTYQRRREGGQEEDACHLPQNQTDGGEVVQDVNSSVQMVMMEQLDPTLLQMKTEVMEGTVAPEAEAAVDDTQIITLQV
Host
Mouse
Reactivity
Human
Interspecies Antigen Sequence
Mouse (97); Rat (97)
Quality Control Testing
Antibody Reactive Against Recombinant Protein.
Western Blot detection against Immunogen (37 KDa) .
Storage Buffer
50 % glycerol
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Cell lysate)
CTCF polyclonal antibody (A01), Lot # 050727JC01 Western Blot analysis of CTCF expression in HL-60 ( Cat # L014V1 ).Western Blot (Recombinant protein)
ELISA
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Gene Info — CTCF
Entrez GeneID
10664GeneBank Accession#
BC014267Protein Accession#
AAH14267Gene Name
CTCF
Gene Alias
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Gene Description
CCCTC-binding factor (zinc finger protein)
Omim ID
604167Gene Ontology
HyperlinkGene Summary
This gene is a member of the BORIS + CTCF gene family and encodes a transcriptional regulator protein with 11 highly conserved zinc finger (ZF) domains. This nuclear protein is able to use different combinations of the ZF domains to bind different DNA target sequences and proteins. Depending upon the context of the site, the protein can bind a histone acetyltransferase (HAT)-containing complex and function as a transcriptional activator or bind a histone deacetylase (HDAC)-containing complex and function as a transcriptional repressor. If the protein is bound to a transcriptional insulator element, it can block communication between enhancers and upstream promoters, thereby regulating imprinted expression. Mutations in this gene have been associated with invasive breast cancers, prostate cancers, and Wilms' tumors. [provided by RefSeq
Other Designations
11 zinc finger transcriptional repressor|11-zinc finger protein|CCCTC-binding factor|CTCFL paralog|transcriptional repressor CTCF
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Interactome
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Disease
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