RGS14 293T Cell Transient Overexpression Lysate(Denatured)
* The price is valid only in USA. Please select country.
-
More Files
- More Functions
-
Specification
Transfected Cell Line
293T
Plasmid
pCMV-RGS14 full-length
Host
Human
Theoretical MW (kDa)
61.4
Quality Control Testing
Transient overexpression cell lysate was tested with Anti-RGS14 antibody (H00010636-B01P) by Western Blots.
SDS-PAGE Gel
RGS14 transfected lysate.
Western Blot
Lane 1: RGS14 transfected lysate ( 61.4 KDa)
Lane 2: Non-transfected lysate.Storage Buffer
1X Sample Buffer (50 mM Tris-HCl, 2% SDS, 10% glycerol, 300 mM 2-mercaptoethanol, 0.01% Bromophenol blue)
Storage Instruction
Store at -80°C. Aliquot to avoid repeated freezing and thawing.
-
Applications
Western Blot
-
Gene Info — RGS14
Entrez GeneID
10636GeneBank Accession#
NM_006480Protein Accession#
NP_006471.2Gene Name
RGS14
Gene Alias
-
Gene Description
regulator of G-protein signaling 14
Omim ID
602513Gene Ontology
HyperlinkGene Summary
This gene encodes a member of the regulator of G-protein signaling family. This protein contains one RGS domain, two Raf-like Ras-binding domains (RBDs), and one GoLoco domain. The protein attenuates the signaling activity of G-proteins by binding, through its GoLoco domain, to specific types of activated, GTP-bound G alpha subunits. Acting as a GTPase activating protein (GAP), the protein increases the rate of conversion of the GTP to GDP. This hydrolysis allows the G alpha subunits to bind G beta/gamma subunit heterodimers, forming inactive G-protein heterotrimers, thereby terminating the signal. Alternate transcriptional splice variants of this gene have been observed but have not been thoroughly characterized. [provided by RefSeq
Other Designations
regulator of G-protein signalling 14
-
Interactome
-
Disease
- +1-909-264-1399
+1-909-992-0619
Toll Free : +1-877-853-6098 - +1-909-992-3401
- sales@abnova.com