NPC2 monoclonal antibody (M01), clone 4B9
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More Files
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Specification
Product Description
Mouse monoclonal antibody raised against a full-length recombinant NPC2.
Immunogen
NPC2 (AAH02532, 1 a.a. ~ 151 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Sequence
MRFLAATFLLLALSTAAQAEPVQFKDCGSVDGVIKEVNVSPCPTQPCQLSKGQSYSVNVTFTSNIQSKSSKAVVHGILMGVPVPFPIPEPDGCKSGINCPIQKDKTYSYLNKLPVKSEYPSIKLVVEWQLQDDKNQSLFCWEIPVQIVSHL
Host
Mouse
Reactivity
Human
Interspecies Antigen Sequence
Mouse (81); Rat (80)
Isotype
IgG2b Kappa
Quality Control Testing
Antibody Reactive Against Recombinant Protein.
Western Blot detection against Immunogen (42.35 KDa) .
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Transfected lysate)
Western Blot analysis of NPC2 expression in transfected 293T cell line by NPC2 monoclonal antibody (M01), clone 4B9.
Lane 1: NPC2 transfected lysate(16.6 KDa).
Lane 2: Non-transfected lysate.
Western Blot (Recombinant protein)
ELISA
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Gene Info — NPC2
Entrez GeneID
10577GeneBank Accession#
BC002532Protein Accession#
AAH02532Gene Name
NPC2
Gene Alias
HE1, MGC1333, NP-C2
Gene Description
Niemann-Pick disease, type C2
Gene Ontology
HyperlinkGene Summary
This gene encodes a protein containing a lipid recognition domain. The encoded protein may function in regulating the transport of cholesterol through the late endosomal/lysosomal system. Mutations in this gene have been associated with Niemann-Pick disease, type C2 and frontal lobe atrophy. [provided by RefSeq
Other Designations
epididymal secretory protein|epididymal secretory protein E1|tissue-specific secretory protein
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Interactome
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Disease
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