CAP1 MaxPab rabbit polyclonal antibody (D01)
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More Files
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Specification
Product Description
Rabbit polyclonal antibody raised against a full-length human CAP1 protein.
Immunogen
CAP1 (NP_006358.1, 1 a.a. ~ 475 a.a) full-length human protein.
Sequence
MADMQNLVERLERAVGRLEAVSHTSDMHRGYADSPSKAGAAPYVQAFDSLLAGPVAEYLKISKEIGGDVQKHAEMVHTGLKLERALLVTASQCQQPAENKLSDLLAPISEQIKEVITFREKNRGSKLFNHLSAVSESIQALGWVAMAPKPGPYVKEMNDAAMFYTNRVLKEYKDVDKKHVDWVKAYLSIWTELQAYIKEFHTTGLAWSKTGPVAKELSGLPSGPSAGSGPPPPPPGPPPPPVSTSSGSDESASRSALFAQINQGESITHALKHVSDDMKTHKNPALKAQSGPVRSGPKPFSAPKPQTSPSPKRATKKEPAVLELEGKKWRVENQENVSNLVIEDTELKQVAYIYKCVNTTLQIKGKINSITVDNCKKLGLVFDDVVGIVEIINSKDVKVQVMGKVPTISINKTDGCHAYLSKNSLDCEIVSAKSSEMNVLIPTEGGDFNEFPVPEQFKTLWNGQKLVTTVTEIAG
Host
Rabbit
Reactivity
Human, Mouse
Interspecies Antigen Sequence
Mouse (95); Rat (95)
Quality Control Testing
Antibody reactive against mammalian transfected lysate.
Storage Buffer
No additive
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Tissue lysate)
CAP1 MaxPab rabbit polyclonal antibody. Western Blot analysis of CAP1 expression in human pancreas.Western Blot (Tissue lysate)
CAP1 MaxPab rabbit polyclonal antibody. Western Blot analysis of CAP1 expression in mouse spleen.Western Blot (Cell lysate)
CAP1 MaxPab rabbit polyclonal antibody. Western Blot analysis of CAP1 expression in HepG2.Western Blot (Transfected lysate)
Western Blot analysis of CAP1 expression in transfected 293T cell line (H00010487-T02) by CAP1 MaxPab polyclonal antibody.
Lane 1: CAP1 transfected lysate(51.70 KDa).
Lane 2: Non-transfected lysate.
Immunoprecipitation
Immunoprecipitation of CAP1 transfected lysate using anti-CAP1 MaxPab rabbit polyclonal antibody and Protein A Magnetic Bead, and immunoblotted with CAP1 purified MaxPab mouse polyclonal antibody (B01P) (H00010487-B01P).Immunofluorescence
Immunofluorescence of purified MaxPab antibody to CAP1 on HeLa cell. [antibody concentration 10 ug/ml] -
Gene Info — CAP1
Entrez GeneID
10487GeneBank Accession#
NM_006367Protein Accession#
NP_006358.1Gene Name
CAP1
Gene Alias
CAP, CAP1-PEN
Gene Description
CAP, adenylate cyclase-associated protein 1 (yeast)
Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene is related to the S. cerevisiae CAP protein, which is involved in the cyclic AMP pathway. The human protein is able to interact with other molecules of the same protein, as well as with CAP2 and actin. Alternatively spliced transcript variants have been identified. [provided by RefSeq
Other Designations
OTTHUMP00000004820|OTTHUMP00000004821|OTTHUMP00000004822|adenylyl cyclase-associated protein
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Interactome
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Disease
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Publication Reference
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A Practical and Analytical Comparative Study of Gel-Based Top-Down and Gel-Free Bottom-Up Proteomics Including Unbiased Proteoform Detection.
Huriye Ercan, Ulrike Resch, Felicia Hsu, Goran Mitulovic, Andrea Bileck, Christopher Gerner, Jae-Won Yang, Margarethe Geiger, Ingrid Miller, Maria Zellner.
Cells 2023 Feb; 12(5):747.
Application:WB-Ce, Human, DU145 cells.
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Structure and mechanism of mouse cyclase-associated protein (CAP1) in regulating actin dynamics.
Jansen S, Collins A, Golden L, Sokolova O, Goode BL.
The Journal of Biological Chemistry 2014 Oct; 289(44):30732.
Application:WB-Ce, Human, HEK293 cells.
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A Practical and Analytical Comparative Study of Gel-Based Top-Down and Gel-Free Bottom-Up Proteomics Including Unbiased Proteoform Detection.
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