PEMT (Human) Recombinant Protein (P01)
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More Files
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Specification
Product Description
Human PEMT full-length ORF ( NP_680477.1, 1 a.a. - 236 a.a.) recombinant protein with GST-tag at N-terminal.
Sequence
MKRSGNPGAEVTNSSVAGPDCCGGLGNIDFRQADFCVMTRLLGYVDPLDPSFVAAVITITFNPLYWNVVARWEHKTRKLSRAFGSPYLACYSLSVTILLLNFLRSHCFTQAMLSQPRMESLDTPAAYSLGLALLGLGVVLVLSSFFALGFAGTFLGDYFGILKEARVTVFPFNILDNPMYWGSTANYLGWAIMHASPTGLLLTVLVALTYIVALLYEEPFTAEIYRQKASGSHKRS
Host
Wheat Germ (in vitro)
Theoretical MW (kDa)
52.3
Interspecies Antigen Sequence
Mouse (80); Rat (80)
Preparation Method
Purification
Glutathione Sepharose 4 Fast Flow
Quality Control Testing
12.5% SDS-PAGE Stained with Coomassie Blue.
Storage Buffer
50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.
Storage Instruction
Store at -80°C. Aliquot to avoid repeated freezing and thawing.
Note
Best use within three months from the date of receipt of this protein.
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Applications
Enzyme-linked Immunoabsorbent Assay
Western Blot (Recombinant protein)
Antibody Production
Protein Array
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Gene Info — PEMT
Entrez GeneID
10400GeneBank Accession#
NM_148172.1Protein Accession#
NP_680477.1Gene Name
PEMT
Gene Alias
MGC2483, PEAMT, PEMPT, PEMT2, PNMT
Gene Description
phosphatidylethanolamine N-methyltransferase
Omim ID
602391Gene Ontology
HyperlinkGene Summary
This gene encodes an enzyme which converts phosphatidylethanolamine to phosphatidylcholine by sequential methylation in the liver. The protein localizes to the endoplasmic reticulum and mitochondria-associated membranes. The gene is within the Smith-Magenis syndrome region on chromosome 17. Alternate splicing of this gene results in three transcript variants encoding two different isoforms. [provided by RefSeq
Other Designations
OTTHUMP00000065536|OTTHUMP00000065537
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Interactome
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