SEMA3A monoclonal antibody (M01), clone 5G9
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Specification
Product Description
Mouse monoclonal antibody raised against a partial recombinant SEMA3A.
Immunogen
SEMA3A (NP_006071, 672 a.a. ~ 770 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Sequence
HLEELLHKDDDGDGSKTKEMSNSMTPSQKVWYRDFMQLINHPNLNTMDEFCEQVWKRDRKQRRQRPGHTPGNSNKWKHLQENKKGRNRRTHEFERAPRS
Host
Mouse
Reactivity
Human
Interspecies Antigen Sequence
Mouse (92); Rat (93)
Isotype
IgG2a Kappa
Quality Control Testing
Antibody Reactive Against Recombinant Protein.
Western Blot detection against Immunogen (36.63 KDa) .
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Recombinant protein)
Sandwich ELISA (Recombinant protein)
Detection limit for recombinant GST tagged SEMA3A is 0.1 ng/ml as a capture antibody.ELISA
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Gene Info — SEMA3A
Entrez GeneID
10371GeneBank Accession#
NM_006080Protein Accession#
NP_006071Gene Name
SEMA3A
Gene Alias
Hsema-I, Hsema-III, MGC133243, SEMA1, SEMAD, SEMAIII, SEMAL, SemD, coll-1
Gene Description
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A
Omim ID
603961Gene Ontology
HyperlinkGene Summary
This gene is a member of the semaphorin family and encodes a protein with an Ig-like C2-type (immunoglobulin-like) domain, a PSI domain and a Sema domain. This secreted protein can function as either a chemorepulsive agent, inhibiting axonal outgrowth, or as a chemoattractive agent, stimulating the growth of apical dendrites. In both cases, the protein is vital for normal neuronal pattern development. Increased expression of this protein is associated with schizophrenia and is seen in a variety of human tumor cell lines. Also, aberrant release of this protein is associated with the progression of Alzheimer's disease. [provided by RefSeq
Other Designations
collapsin 1|semaphorin 3A|semaphorin D|semaphorin III|semaphorin L|semaphorin-like
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Interactome
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Pathway
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Disease
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