APBB3 rabbit monoclonal antibody
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Specification
Product Description
Rabbit monoclonal antibody raised against a human APBB3 peptide using ARM Technology.
Immunogen
A synthetic peptide of human APBB3 is used for rabbit immunization.
Customer or Abnova will decide on the preferred peptide sequence.Host
Rabbit
Library Construction
Non-fusion antibody library from rabbit spleen (ARM Technology).
Expression
Overexpression vector and transfection into 293H cell line.
Reactivity
Human
Purification
Protein A
Isotype
IgG
Quality Control Testing
Antibody reactive against human APBB3 peptide by ELISA and mammalian transfected lysate by Western Blot.
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
Deliverable
Up to three rabbit IgG clones of 100 ug each will be delivered to customer.
Note
1. Customer may provide cell or tissue lysate for antibody screening.
2. Rabbit monoclonal antibody generated by ARM technology is amenable to antibody engineering including F(ab)2, IgG, scFv and different Fc and non-Fc conjugates per customer request. -
Applications
Western Blot (Transfected lysate)
ELISA
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Gene Info — APBB3
Entrez GeneID
10307GeneBank Accession#
APBB3Gene Name
APBB3
Gene Alias
FE65L2, MGC150555, MGC87674, SRA
Gene Description
amyloid beta (A4) precursor protein-binding, family B, member 3
Omim ID
602711Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene is a member of the APBB protein family. It is found in the cytoplasm and binds to the intracellular domain of the Alzheimer's disease beta-amyloid precursor protein (APP) as well as to other APP-like proteins. It is thought that the protein encoded by this gene may modulate the internalization of APP. Multiple transcript variants encoding several different isoforms have been found for this gene. [provided by RefSeq
Other Designations
FE65-like protein 2|amyloid beta precursor protein-binding, family B, member 3|amyloid precursor interacting protein
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Interactome
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