RAMP3 DNAxPab
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Specification
Product Description
Rabbit polyclonal antibody raised against a partial-length human RAMP3 DNA using DNAx™ Immune technology.
Technology
Immunogen
RAMP3 (NP_005847.1, 24 a.a. ~ 118 a.a) partial-length human DNA
Sequence
RAGGCNETGMLERLPLCGKAFADMMGKVDVWKWCNLSEFIVYYESFTNCTEMEANVVGCYWPNPLAQGFITGIHRQFFSNCTVDRVHLEDPPDEV
Host
Rabbit
Reactivity
Human
Purification
Protein A
Quality Control Testing
Antibody reactive against mammalian transfected lysate.
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Transfected lysate)
Western Blot analysis of RAMP3 expression in transfected 293T cell line by RAMP3 DNAxPab polyclonal antibody.
Lane 1: RAMP3 transfected lysate(31.57 KDa).
Lane 2: Non-transfected lysate.
Immunofluorescence (Transfected cell)
Flow Cytometry (Transfected cell)
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Gene Info — RAMP3
Entrez GeneID
10268GeneBank Accession#
NM_005856.1Protein Accession#
NP_005847.1Gene Name
RAMP3
Gene Alias
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Gene Description
receptor (G protein-coupled) activity modifying protein 3
Omim ID
605155Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene is a member of the RAMP family of single-transmembrane-domain proteins, called receptor (calcitonin) activity modifying proteins (RAMPs). RAMPs are type I transmembrane proteins with an extracellular N terminus and a cytoplasmic C terminus. RAMPs are required to transport calcitonin-receptor-like receptor (CRLR) to the plasma membrane. CRLR, a receptor with seven transmembrane domains, can function as either a calcitonin-gene-related peptide (CGRP) receptor or an adrenomedullin receptor, depending on which members of the RAMP family are expressed. In the presence of this (RAMP3) protein, CRLR functions as an adrenomedullin receptor. [provided by RefSeq
Other Designations
calcitonin receptor-like receptor activity modifying protein 3|receptor (calcitonin) activity modifying protein 3|receptor activity modifying protein 3|receptor-activity-modifying protein 3
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Interactome
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Pathway
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Disease
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