RAMP2 DNAxPab
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Specification
Product Description
Rabbit polyclonal antibody raised against a partial-length human RAMP2 DNA using DNAx™ Immune technology.
Technology
Immunogen
Extracellular membrane domain (ECD) human DNA
Host
Rabbit
Reactivity
Human
Purification
Protein A
Quality Control Testing
Antibody reactive against mammalian transfected lysate.
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Transfected lysate)
Immunofluorescence (Transfected cell)
Flow Cytometry (Transfected cell)
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Gene Info — RAMP2
Entrez GeneID
10266GeneBank Accession#
NM_005854.2Protein Accession#
NP_005845.2Gene Name
RAMP2
Gene Alias
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Gene Description
receptor (G protein-coupled) activity modifying protein 2
Omim ID
605154Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene is a member of the RAMP family of single-transmembrane-domain proteins, called receptor (calcitonin) activity modifying proteins (RAMPs). RAMPs are type I transmembrane proteins with an extracellular N terminus and a cytoplasmic C terminus. RAMPs are required to transport calcitonin-receptor-like receptor (CRLR) to the plasma membrane. CRLR, a receptor with seven transmembrane domains, can function as either a calcitonin-gene-related peptide (CGRP) receptor or an adrenomedullin receptor, depending on which members of the RAMP family are expressed. In the presence of this (RAMP2) protein, CRLR functions as an adrenomedullin receptor. The RAMP2 protein is involved in core glycosylation and transportation of adrenomedullin receptor to the cell surface. [provided by RefSeq
Other Designations
calcitonin receptor-like receptor activity modifying protein 2|receptor (calcitonin) activity modifying protein 2|receptor activity modifying protein 2|receptor-activity-modifying protein 2
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Interactome
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Pathway
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Disease
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