SPRY2 purified MaxPab rabbit polyclonal antibody (D01P)
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More Files
- More Functions
Western Blot (Cell lysate)
SPRY2 MaxPab rabbit polyclonal antibody. Western Blot analysis of SPRY2 expression in HeLa.
Western Blot (Transfected lysate)
Western Blot analysis of SPRY2 expression in transfected 293T cell line (H00010253-T02) by SPRY2 MaxPab polyclonal antibody.
Lane 1: SPRY2 transfected lysate(34.70 KDa).
Lane 2: Non-transfected lysate.
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Specification
Product Description
Rabbit polyclonal antibody raised against a full-length human SPRY2 protein.
Immunogen
SPRY2 (NP_005833.1, 1 a.a. ~ 315 a.a) full-length human protein.
Sequence
MEARAQSGNGSQPLLQTPRDGGRQRGEPDPRDALTQQVHVLSLDQIRAIRNTNEYTEGPTVVPRPGLKPAPRPSTQHKHERLHGLPEHRQPPRLQHSQVHSSARAPLSRSISTVSSGSRSSTRTSTSSSSSEQRLLGSSFSSGPVADGIIRVQPKSELKPGELKPLSKEDLGLHAYRCEDCGKCKCKECTYPRPLPSDWICDKQCLCSAQNVIDYGTCVCCVKGLFYHCSNDDEDNCADNPCSCSQSHCCTRWSAMGVMSLFLPCLWCYLPAKGCLKLCQGCYDRVNRPGCRCKNSNTVCCKVPTVPPRNFEKPT
Host
Rabbit
Reactivity
Human
Interspecies Antigen Sequence
Mouse (96); Rat (95)
Quality Control Testing
Antibody reactive against mammalian transfected lysate.
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Cell lysate)
SPRY2 MaxPab rabbit polyclonal antibody. Western Blot analysis of SPRY2 expression in HeLa.Western Blot (Transfected lysate)
Western Blot analysis of SPRY2 expression in transfected 293T cell line (H00010253-T02) by SPRY2 MaxPab polyclonal antibody.
Lane 1: SPRY2 transfected lysate(34.70 KDa).
Lane 2: Non-transfected lysate.
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Gene Info — SPRY2
Entrez GeneID
10253GeneBank Accession#
NM_005842Protein Accession#
NP_005833.1Gene Name
SPRY2
Gene Alias
MGC23039, hSPRY2
Gene Description
sprouty homolog 2 (Drosophila)
Omim ID
602466Gene Ontology
HyperlinkGene Summary
This gene encodes a protein belonging to the sprouty family. The encoded protein contains a carboxyl-terminal cysteine-rich domain essential for the inhibitory activity on receptor tyrosine kinase signaling proteins and is required for growth factor stimulated translocation of the protein to membrane ruffles. In primary dermal endothelial cells this gene is transiently upregulated in response to fibroblast growth factor two. This protein is indirectly involved in the non-cell autonomous inhibitory effect on fibroblast growth factor two signaling. The protein interacts with Cas-Br-M (murine) ectropic retroviral transforming sequence, and can function as a bimodal regulator of epidermal growth factor receptor/mitogen-activated protein kinase signaling. This protein may play a role in alveoli branching during lung development as shown by a similar mouse protein. [provided by RefSeq
Other Designations
OTTHUMP00000018543|OTTHUMP00000018544|sprouty 2
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