RASGRP2 purified MaxPab rabbit polyclonal antibody (D01P)
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More Files
- More Functions
Western Blot (Tissue lysate)
RASGRP2 MaxPab rabbit polyclonal antibody. Western Blot analysis of RASGRP2 expression in human stomach.
Western Blot (Transfected lysate)
Western Blot analysis of RASGRP2 expression in transfected 293T cell line (H00010235-T02) by RASGRP2 MaxPab polyclonal antibody.
Lane 1: RASGRP2 transfected lysate(75.50 KDa).
Lane 2: Non-transfected lysate.
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Specification
Product Description
Rabbit polyclonal antibody raised against a full-length human RASGRP2 protein.
Immunogen
RASGRP2 (NP_005816.2, 1 a.a. ~ 671 a.a) full-length human protein.
Sequence
MGTQRLCGRGTQGWPGSSEQHVQEATSSAGLHSGVDELGVRSEPGGRLPERSLGPAHPAPAAMAGTLDLDKGCTVEELLRGCIEAFDDSGKVRDPQLVRMFLMMHPWYIPSSQLAAKLLHIYQQSRKDNSNSLQVKTCHLVRYWISAFPAEFDLNPELAEQIKELKALLDQEGNRRHSSLIDIDSVPTYKWKRQVTQRNPVGQKKRKMSLLFDHLEPMELAEHLTYLEYRSFCKILFQDYHSFVTHGCTVDNPVLERFISLFNSVSQWVQLMILSKPTAPQRALVITHFVHVAEKLLQLQNFNTLMAVVGGLSHSSISRLKETHSHVSPETIKLWEGLTELVTATGNYGNYRRRLAACVGFRFPILGVHLKDLVALQLALPDWLDPARTRLNGAKMKQLFSILEELAMVTSLRPPVQANPDLLSLLTVSLDQYQTEDELYQLSLQREPRSKSSPTSPTSCTPPPRPPVLEEWTSAAKPKLDQALVVEHIEKMVESVFRNFDVDGDGHISQEEFQIIRGNFPYLSAFGDLDQNQDGCISREEMVSYFLRSSSVLGGRMGFVHNFQESNSLRPVACRHCKALILGIYKQGLKCRACGVNCHKQCKDRLSVECRRRAQSVSLEGSAPSPSPMHSHHHRAFSFSLPRPGRRGSRPPEIREEEVQTVEDGVFDIHL
Host
Rabbit
Reactivity
Human
Interspecies Antigen Sequence
Mouse (96)
Quality Control Testing
Antibody reactive against mammalian transfected lysate.
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Tissue lysate)
RASGRP2 MaxPab rabbit polyclonal antibody. Western Blot analysis of RASGRP2 expression in human stomach.Western Blot (Transfected lysate)
Western Blot analysis of RASGRP2 expression in transfected 293T cell line (H00010235-T02) by RASGRP2 MaxPab polyclonal antibody.
Lane 1: RASGRP2 transfected lysate(75.50 KDa).
Lane 2: Non-transfected lysate.
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Gene Info — RASGRP2
Entrez GeneID
10235GeneBank Accession#
NM_005825Protein Accession#
NP_005816.2Gene Name
RASGRP2
Gene Alias
CALDAG-GEFI, CDC25L
Gene Description
RAS guanyl releasing protein 2 (calcium and DAG-regulated)
Omim ID
605577Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene is a brain-enriched nucleotide exchanged factor that contains an N-terminal GEF domain, 2 tandem repeats of EF-hand calcium-binding motifs, and a C-terminal diacylglycerol/phorbol ester-binding domain. This protein can activate small GTPases, including RAS and RAP1/RAS3. The nucleotide exchange activity of this protein can be stimulated by calcium and diacylglycerol. Three alternatively spliced transcript variants encoding the same protein have been found for this gene. [provided by RefSeq
Other Designations
OTTHUMP00000042931|OTTHUMP00000069245|OTTHUMP00000069246|RAS guanyl nucleotide-releasing protein 2|RAS guanyl releasing protein 2|calcium and DAG-regulated guanine nucleotide exchange factor I|calcium and diacylglycerol-regulated guanine nucleotide exchan
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Interactome
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Pathway
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