CD96 monoclonal antibody (M01), clone 3H8
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More Files
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Specification
Product Description
Mouse monoclonal antibody raised against a full length recombinant CD96.
Immunogen
CD96 (AAH20749, 1 a.a. ~ 402 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Sequence
MEKKWKYCAVYYIIQIHFVKGVWEKTVNTEENVYATLGSDVNLTCQTQTVGFFVQMQWSKVTNKIDLIAVYHPQYGFYCAYGRPCESLVTFTETPENGSRWTLHLRNMSCSVSGRYECMLVLYPEGIQTKIYNLLIQTHVTADEWNSNHTIEIEINQTLEIPCFQNSSSKISSEFTYAWSVEDNGTQETLISQNHLISNSTLLKDRVKLGTDYRLHLSPVQIFDDGRKFSCHIRVGPNKILRSSTTVKVFAKPEIPVIVENNSTDVLVERRFTCLLKNVFPKANITWFIDGSFLHDEKEGIYITNEERKGKDGFLELKSVLTRVHSNKPAQSDNLTIWCMALSPVPGNKVWNISSGKITFLLGSEISSTDPPLSVTESTLDTQPSPASSVSPASKNVFTLSY
Host
Mouse
Reactivity
Human
Interspecies Antigen Sequence
Mouse (60); Rat (58)
Isotype
IgG2a Kappa
Quality Control Testing
Antibody Reactive Against Recombinant Protein.
Western Blot detection against Immunogen (69.96 KDa) .
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Recombinant protein)
Sandwich ELISA (Recombinant protein)
Detection limit for recombinant GST tagged CD96 is approximately 3ng/ml as a capture antibody.ELISA
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Gene Info — CD96
Entrez GeneID
10225GeneBank Accession#
BC020749Protein Accession#
AAH20749Gene Name
CD96
Gene Alias
DKFZp667E2122, MGC22596, TACTILE
Gene Description
CD96 molecule
Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene belongs to the immunoglobulin superfamily. It is a type I membrane protein. The protein may play a role in the adhesive interactions of activated T and NK cells during the late phase of the immune response. It may also function in antigen presentation. Alternative splicing occurs at this locus and two transcript variants encoding distinct isoforms have been identified. [provided by RefSeq
Other Designations
CD96 antigen|T cell activation, increased late expression|T-cell surface protein tactile
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Interactome
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Disease
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Publication Reference
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Interaction between nectin-1 and the human natural killer cell receptor CD96.
Holmes VM, Maluquer de Motes C, Richards PT, Roldan J, Bhargava AK, Orange JS, Krummenacher C.
PLoS One 2019 Feb; 14(2):e0212443.
Application:ELISA, Human, Recombinant protein.
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Interaction between nectin-1 and the human natural killer cell receptor CD96.
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