USH1C monoclonal antibody (M07), clone 2B3
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More Files
- More Functions
Western Blot (Transfected lysate)
Western Blot analysis of USH1C expression in transfected 293T cell line by USH1C monoclonal antibody (M07), clone 2B3.
Lane 1: USH1C transfected lysate (Predicted MW: 60.3 KDa).
Lane 2: Non-transfected lysate.
Immunoprecipitation
Immunoprecipitation of USH1C transfected lysate using anti-USH1C monoclonal antibody and Protein A Magnetic Bead, and immunoblotted with USH1C monoclonal antibody.
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Specification
Product Description
Mouse monoclonal antibody raised against a partial recombinant USH1C.
Immunogen
USH1C (AAH16057, 424 a.a. ~ 533 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Sequence
FTPEQIMGKDVRLLRIKKEGSLDLALEGGVDSPIGKVVVSAVYERGAAERHGGIVKGDEIMAINGKIVTDYTLAEADAALQKAWNQGGDWIDLVVAVCPPKEYDDELTFF
Host
Mouse
Reactivity
Human
Interspecies Antigen Sequence
Mouse (91)
Isotype
IgG2a Kappa
Quality Control Testing
Antibody Reactive Against Recombinant Protein.
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Transfected lysate)
Western Blot analysis of USH1C expression in transfected 293T cell line by USH1C monoclonal antibody (M07), clone 2B3.
Lane 1: USH1C transfected lysate (Predicted MW: 60.3 KDa).
Lane 2: Non-transfected lysate.
Immunoprecipitation
Immunoprecipitation of USH1C transfected lysate using anti-USH1C monoclonal antibody and Protein A Magnetic Bead, and immunoblotted with USH1C monoclonal antibody.ELISA
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Gene Info — USH1C
Entrez GeneID
10083GeneBank Accession#
BC016057Protein Accession#
AAH16057Gene Name
USH1C
Gene Alias
AIE-75, DFNB18, NY-CO-37, NY-CO-38, PDZ-45, PDZ-73, PDZ-73/NY-CO-38, PDZ73, ush1cpst
Gene Description
Usher syndrome 1C (autosomal recessive, severe)
Gene Ontology
HyperlinkGene Summary
This gene encodes a scaffold protein that functions in the assembly of Usher protein complexes. The protein contains PDZ domains, a coiled-coil region with a bipartite nuclear localization signal and a PEST degradation sequence. Defects in this gene are the cause of Usher syndrome type 1C and non-syndromic sensorineural deafness autosomal recessive type 18. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq
Other Designations
harmonin
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Interactome
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Disease
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