IL18BP DNAxPab
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Specification
Product Description
Rabbit polyclonal antibody raised against a partial-length human IL18BP DNA using DNAx™ Immune technology.
Technology
Immunogen
Extracellular membrane domain (ECD) human DNA
Host
Rabbit
Reactivity
Human
Purification
Protein A
Quality Control Testing
Antibody reactive against mammalian transfected lysate.
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Transfected lysate)
Immunofluorescence (Transfected cell)
Flow Cytometry (Transfected cell)
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Gene Info — IL18BP
Entrez GeneID
10068GeneBank Accession#
BC044215Protein Accession#
AAH44215Gene Name
IL18BP
Gene Alias
IL18BPa
Gene Description
interleukin 18 binding protein
Omim ID
604113Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene is an inhibitor of the proinflammatory cytokine IL18. This protein binds to IL18, prevents the binding of IL18 to its receptor, and thus inhibits IL18-induced IFN-gamma production. This protein is constitutively expressed and secreted in mononuclear cells. The expression of this protein can be enhanced by IFN-gamma. An elevated level of this protein is detected in the intestinal tissues of patients with Crohn's disease. Alternative splicing results in multiple transcript variants. [provided by RefSeq
Other Designations
MC51L-53L-54L homolog gene product|OTTHUMP00000179141|OTTHUMP00000179143
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Disease
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