PDCD6 monoclonal antibody (M01J), clone 2B4
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Specification
Product Description
Mouse monoclonal antibody raised against a partial recombinant PDCD6.
This product is belong to Cell Culture Grade Antibody (CX Grade).Immunogen
PDCD6 (AAH12384.1, 92 a.a. ~ 191 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Sequence
ITDWQNVFRTYDRDNSGMIDKNELKQALSGFGYRLSDQFHDILIRKFDRQGRGQIAFDDFIQGCIVLQRLTDIFRRYDTDQDGWIQVSYEQYLSMVFSIV
Host
Mouse
Reactivity
Human
Preparation Method
Cell Culture Production
Isotype
IgG2a Kappa
Quality Control Testing
Antibody Reactive Against Recombinant Protein.
Western Blot detection against Immunogen (36.63 KDa) .
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Recombinant protein)
ELISA
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Gene Info — PDCD6
Entrez GeneID
10016GeneBank Accession#
BC012384.1Protein Accession#
AAH12384.1Gene Name
PDCD6
Gene Alias
ALG-2, FLJ46208, MGC111017, MGC119050, MGC9123, PEF1B
Gene Description
programmed cell death 6
Omim ID
601057Gene Ontology
HyperlinkGene Summary
This gene encodes a calcium-binding protein belonging to the penta-EF-hand protein family. Calcium binding is important for homodimerization and for conformational changes required for binding to other protein partners. This gene product participates in T cell receptor-, Fas-, and glucocorticoid-induced programmed cell death. In mice deficient for this gene product, however, apoptosis was not blocked suggesting this gene product is functionally redundant. [provided by RefSeq
Other Designations
apoptosis-linked gene 2|apoptosis-linked gene-2
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