REC8 monoclonal antibody (M01), clone 2G3
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More Files
- More Functions
Sandwich ELISA (Recombinant protein)
Detection limit for recombinant GST tagged REC8L1 is approximately 3ng/ml as a capture antibody.
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Specification
Product Description
Mouse monoclonal antibody raised against a partial recombinant REC8.
Immunogen
REC8 (AAH04159.1, 1 a.a. ~ 110 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Sequence
MFYYPNVLQRHTGCFATIWLAATRGSRLVKREYLRVNVVKTCEEILNYVLVRVQPPQPGLPRPRFSLYLSAQLQIGVIRVYSQQCQYLVEDIQHILERLHRAQLQIRIDM
Host
Mouse
Reactivity
Human
Interspecies Antigen Sequence
Mouse (70); Rat (70)
Isotype
IgG2a Kappa
Quality Control Testing
Antibody Reactive Against Recombinant Protein.
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Sandwich ELISA (Recombinant protein)
Detection limit for recombinant GST tagged REC8L1 is approximately 3ng/ml as a capture antibody.ELISA
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Gene Info — REC8
Entrez GeneID
9985GeneBank Accession#
BC004159Protein Accession#
AAH04159.1Gene Name
REC8
Gene Alias
HR21spB, MGC950, REC8L1, Rec8p
Gene Description
REC8 homolog (yeast)
Omim ID
608193Gene Ontology
HyperlinkGene Summary
This gene encodes a member of the kleisin family of SMC (structural maintenance of chromosome) protein partners. The protein localizes to the axial elements of chromosomes during meiosis in both oocytes and spermatocytes. In the mouse, the homologous protein is a key component of the meiotic cohesion complex, which regulates sister chromatid cohesion and recombination between homologous chromosomes. Multiple alternatively spliced variants, encoding the same protein, have been found for this gene. [provided by RefSeq
Other Designations
REC8 homolog|REC8-like 1|cohesion rec8p|human homolog of rad21, S. pombe|meiotic recombination and sister chromatid cohesion phosphoprotein of the rad21p family|meiotic recombination protein REC8-like 1|recombination and sister chromatid cohesion protein
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Interactome
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Disease
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