MAML1 polyclonal antibody (A01)
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More Files
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Specification
Product Description
Mouse polyclonal antibody raised against a partial recombinant MAML1.
Immunogen
MAML1 (NP_055572, 655 a.a. ~ 754 a.a) partial recombinant protein with GST tag.
Sequence
AEQEKQQFQRHLTRPPPQYQDPTQGSFPQQVGQFTGSSAAVPGMNTLGPSNSSCPRVFPQAGNLMPMGPGHASVSSLPTNSGQQDRGVAQFPGSQNMPQS
Host
Mouse
Reactivity
Human
Interspecies Antigen Sequence
Mouse (86); Rat (84)
Quality Control Testing
Antibody Reactive Against Recombinant Protein.
Western Blot detection against Immunogen (37.11 KDa) .
Storage Buffer
50 % glycerol
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Recombinant protein)
ELISA
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Gene Info — MAML1
Entrez GeneID
9794GeneBank Accession#
NM_014757Protein Accession#
NP_055572Gene Name
MAML1
Gene Alias
KIAA0200, Mam-1, Mam1
Gene Description
mastermind-like 1 (Drosophila)
Omim ID
605424Gene Ontology
HyperlinkGene Summary
This protein is the human homolog of mastermind, a Drosophila protein that plays a role in the Notch signaling pathway involved in cell-fate determination. There is in vitro evidence that the human homolog forms a complex with the intracellular portion of human Notch receptors and can increase expression of a Notch-induced gene. This evidence supports its proposed function as a transcriptional co-activator in the Notch signaling pathway. [provided by RefSeq
Other Designations
mastermind homolog|mastermind-like 1
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Interactome
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Pathway
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Disease
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