HDAC4 293T Cell Transient Overexpression Lysate(Denatured)
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More Files
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SDS-PAGE Gel
HDAC4 transfected lysate.
Western Blot
Lane 1: HDAC4 transfected lysate ( 106.4 KDa)
Lane 2: Non-transfected lysate.
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Specification
Transfected Cell Line
293T
Plasmid
pCMV-HDAC4 full-length
Host
Human
Theoretical MW (kDa)
106.4
Interspecies Antigen Sequence
Mouse (92); Rat (92)
Quality Control Testing
Transient overexpression cell lysate was tested with Anti-HDAC4 antibody (H00009759-B01) by Western Blots.
SDS-PAGE Gel
HDAC4 transfected lysate.
Western Blot
Lane 1: HDAC4 transfected lysate ( 106.4 KDa)
Lane 2: Non-transfected lysate.Storage Buffer
1X Sample Buffer (50 mM Tris-HCl, 2% SDS, 10% glycerol, 300 mM 2-mercaptoethanol, 0.01% Bromophenol blue)
Storage Instruction
Store at -80°C. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot
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Gene Info — HDAC4
Entrez GeneID
9759GeneBank Accession#
BC039904.1Protein Accession#
AAH39904.1Gene Name
HDAC4
Gene Alias
HA6116, HD4, HDAC-A, HDACA, KIAA0288
Gene Description
histone deacetylase 4
Omim ID
605314Gene Ontology
HyperlinkGene Summary
Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation/deacetylation alters chromosome structure and affects transcription factor access to DNA. The protein encoded by this gene belongs to class II of the histone deacetylase/acuc/apha family. It possesses histone deacetylase activity and represses transcription when tethered to a promoter. This protein does not bind DNA directly, but through transcription factors MEF2C and MEF2D. It seems to interact in a multiprotein complex with RbAp48 and HDAC3. [provided by RefSeq
Other Designations
histone deacetylase A
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Interactome
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Disease
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