LRAT monoclonal antibody (M05), clone 4E12
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Specification
Product Description
Mouse monoclonal antibody raised against a partial recombinant LRAT.
Immunogen
LRAT (NP_004735.2, 33 a.a. ~ 132 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Sequence
DKGRNSFYETSSFHRGDVLEVPRTHLTHYGIYLGDNRVAHMMPDILLALTDDMGRTQKVVSNKRLILGVIVKVASIRVDTVEDFAYGANILVNHLDESLQ
Host
Mouse
Reactivity
Human
Interspecies Antigen Sequence
Mouse (80); Rat (78)
Isotype
IgG2a Kappa
Quality Control Testing
Antibody Reactive Against Recombinant Protein.
Western Blot detection against Immunogen (36.74 KDa) .
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Recombinant protein)
Sandwich ELISA (Recombinant protein)
Detection limit for recombinant GST tagged LRAT is 0.3 ng/ml as a capture antibody.ELISA
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Gene Info — LRAT
Entrez GeneID
9227GeneBank Accession#
NM_004744Protein Accession#
NP_004735.2Gene Name
LRAT
Gene Alias
MGC33103
Gene Description
lecithin retinol acyltransferase (phosphatidylcholine--retinol O-acyltransferase)
Omim ID
604863Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene is a microsomal enzyme that catalyzes the esterification of all-trans-retinol into all-trans-retinyl ester, an essential reaction for the retinoid cycle in visual system and vitamin A status in liver. Mutations in this gene have been associated with early-onset severe retinal dystrophy. [provided by RefSeq
Other Designations
lecithin retinol acyltransferase
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Interactome
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Pathway
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Disease
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