OSMR 293T Cell Transient Overexpression Lysate(Denatured)
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Specification
Transfected Cell Line
293T
Plasmid
pCMV-OSMR full-length
Host
Human
Theoretical MW (kDa)
37.73
Quality Control Testing
Transient overexpression cell lysate was tested with Anti-OSMR antibody (H00009180-B01) by Western Blots.
Western Blot
Lane 1: OSMR transfected lysate ( 39.5 KDa)
Lane 2: Non-transfected lysate.SDS-PAGE Gel
OSMR transfected lysate.
Storage Buffer
1X Sample Buffer (50 mM Tris-HCl, 2% SDS, 10% glycerol, 300 mM 2-mercaptoethanol, 0.01% Bromophenol blue)
Storage Instruction
Store at -80°C. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot
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Gene Info — OSMR
Entrez GeneID
9180GeneBank Accession#
BC010943Protein Accession#
AAH10943Gene Name
OSMR
Gene Alias
MGC150626, MGC150627, MGC75127, OSMRB
Gene Description
oncostatin M receptor
Omim ID
601743Gene Ontology
HyperlinkGene Summary
Oncostatin M is a member of the IL6 family of cytokines. Functional receptors for IL6 family cytokines are multisubunit complexes involving members of the hematopoietin receptor superfamily. Many IL6 cytokines utilize gp130 as a common receptor subunit. OSM binds to the gp130 receptor subunit and, in association with the leukemia inhibitory factor receptor, induces a proliferative response in permissive cells. OSMR is an alternative subunit (for an OSM receptor complex (a heterodimer of gp130 and OSMR) that is activated by OSM but not by LIF [provided by RefSeq
Other Designations
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