DIRAS3 rabbit monoclonal antibody
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Specification
Product Description
Rabbit monoclonal antibody raised against a human DIRAS3 peptide using ARM Technology.
Immunogen
A synthetic peptide of human DIRAS3 is used for rabbit immunization.
Customer or Abnova will decide on the preferred peptide sequence.Host
Rabbit
Library Construction
Non-fusion antibody library from rabbit spleen (ARM Technology).
Expression
Overexpression vector and transfection into 293H cell line.
Reactivity
Human
Purification
Protein A
Isotype
IgG
Quality Control Testing
Antibody reactive against human DIRAS3 peptide by ELISA and mammalian transfected lysate by Western Blot.
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
Deliverable
Up to three rabbit IgG clones of 100 ug each will be delivered to customer.
Note
1. Customer may provide cell or tissue lysate for antibody screening.
2. Rabbit monoclonal antibody generated by ARM technology is amenable to antibody engineering including F(ab)2, IgG, scFv and different Fc and non-Fc conjugates per customer request. -
Applications
Western Blot (Transfected lysate)
ELISA
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Gene Info — DIRAS3
Entrez GeneID
9077GeneBank Accession#
DIRAS3Gene Name
DIRAS3
Gene Alias
ARHI, NOEY2
Gene Description
DIRAS family, GTP-binding RAS-like 3
Omim ID
605193Gene Ontology
HyperlinkGene Summary
This gene is a member of the ras superfamily, and is expressed in normal ovarian and breast epithelial cells but not in ovarian and breast cancers. It is a maternally imprinted gene and its expression is associated with growth suppression. Thus, this gene appears to be a putative tumor suppressor gene whose function is abrogated in ovarian and breast cancers. [provided by RefSeq
Other Designations
OTTHUMP00000011138|ras homolog gene family, member I
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Interactome
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Disease
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