CLDN8 (Human) Recombinant Protein (Q01)
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Specification
Product Description
Human CLDN8 partial ORF ( NP_955360, 29 a.a. - 81 a.a.) recombinant protein with GST-tag at N-terminal.
Sequence
QWRVSAFIENNIVVFENFWEGLWMNCVRQANIRMQCKIYDSLLALSPDLQAAR
Host
Wheat Germ (in vitro)
Theoretical MW (kDa)
31.57
Interspecies Antigen Sequence
Mouse (82); Rat (83)
Preparation Method
Purification
Glutathione Sepharose 4 Fast Flow
Quality Control Testing
12.5% SDS-PAGE Stained with Coomassie Blue.
Storage Buffer
50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.
Storage Instruction
Store at -80°C. Aliquot to avoid repeated freezing and thawing.
Note
Best use within three months from the date of receipt of this protein.
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Applications
Enzyme-linked Immunoabsorbent Assay
Western Blot (Recombinant protein)
Antibody Production
Protein Array
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Gene Info — CLDN8
Entrez GeneID
9073GeneBank Accession#
NM_199328Protein Accession#
NP_955360Gene Name
CLDN8
Gene Alias
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Gene Description
claudin 8
Omim ID
611231Gene Ontology
HyperlinkGene Summary
Claudins, such as CLDN8, are components of epithelial cell tight junctions. Tight junctions regulate movement of solutes and ions through the paracellular space and prevent mixing of proteins and lipids in the outer leaflet of the apical and basolateral plasma membrane domains (Acharya et al., 2004).[supplied by OMIM
Other Designations
OTTHUMP00000101915
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Interactome
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Pathway
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