CH25H polyclonal antibody (A01)
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Specification
Product Description
Mouse polyclonal antibody raised against a partial recombinant CH25H.
Immunogen
CH25H (NP_003947, 206 a.a. ~ 272 a.a) partial recombinant protein with GST tag.
Sequence
VNIWLSVEDHSGYNFPWSTHRLVPFGWYGGVVHHDLHHSHFNCNFAPYFTHWDKILGTLRTASVPAR
Host
Mouse
Reactivity
Human
Interspecies Antigen Sequence
Mouse (78); Rat (81)
Quality Control Testing
Antibody Reactive Against Recombinant Protein.
Western Blot detection against Immunogen (33.48 KDa) .
Storage Buffer
50 % glycerol
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Recombinant protein)
ELISA
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Gene Info — CH25H
Entrez GeneID
9023GeneBank Accession#
NM_003956Protein Accession#
NP_003947Gene Name
CH25H
Gene Alias
C25H
Gene Description
cholesterol 25-hydroxylase
Omim ID
604551Gene Ontology
HyperlinkGene Summary
This is an intronless gene that is involved in cholesterol and lipid metabolism. The encoded protein is a membrane protein and contains clusters of histidine residues essential for catalytic activity. Unlike most other sterol hydroxylases, this enzyme is a member of a small family of enzymes that utilize diiron cofactors to catalyze the hydroxylation of hydrophobic substrates. [provided by RefSeq
Other Designations
OTTHUMP00000020057
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Interactome
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Pathway
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Disease
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Publication Reference
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Increased 25-hydroxycholesterol concentrations in the lungs of patients with chronic obstructive pulmonary disease.
Sugiura H, Koarai A, Ichikawa T, Minakata Y, Matsunaga K, Hirano T, Akamatsu K, Yanagisawa S, Furusawa M, Uno Y, Yamasaki M, Satomi Y, Ichinose M.
Respirology 2012 Apr; 17(3):533.
Application:IHC, Human, Human lung tissues.
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Increased 25-hydroxycholesterol concentrations in the lungs of patients with chronic obstructive pulmonary disease.
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