CES2 (Human) Recombinant Protein (Q01)
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More Files
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Specification
Product Description
Human CES2 partial ORF ( NP_003860, 514 a.a. - 621 a.a.) recombinant protein with GST-tag at N-terminal.
Sequence
PPHMKADHGDELPFVFRSFFGGNYIKFTEEEEQLSRKMMKYWANFARNGNPNGEGLPHWPLFDQEEQYLQLNLQPAVGRALKAHRLQFWKKALPQKIQELEEPEERHT
Host
Wheat Germ (in vitro)
Theoretical MW (kDa)
37.62
Interspecies Antigen Sequence
Mouse (72); Rat (73)
Preparation Method
Purification
Glutathione Sepharose 4 Fast Flow
Quality Control Testing
12.5% SDS-PAGE Stained with Coomassie Blue.
Storage Buffer
50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.
Storage Instruction
Store at -80°C. Aliquot to avoid repeated freezing and thawing.
Note
Best use within three months from the date of receipt of this protein.
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Applications
Enzyme-linked Immunoabsorbent Assay
Western Blot (Recombinant protein)
Antibody Production
Protein Array
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Gene Info — CES2
Entrez GeneID
8824GeneBank Accession#
NM_003869Protein Accession#
NP_003860Gene Name
CES2
Gene Alias
CE-2, CES2A1, PCE-2, iCE
Gene Description
carboxylesterase 2 (intestine, liver)
Omim ID
605278Gene Ontology
HyperlinkGene Summary
Carboxylesterase 2 is a member of a large multigene family. The enzymes encoded by these genes are responsible for the hydrolysis of ester- and amide-bond-containing drugs such as cocaine and heroin. They also hydrolize long-chain fatty acid esters and thioesters. The specific function of this enzyme has not yet been determined; however, it is speculated that carboxylesterases may play a role in lipid metabolism and/or the blood-brain barrier system. Two alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. [provided by RefSeq
Other Designations
carboxylesterase 2|intestinal carboxylesterase; liver carboxylesterase-2
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Interactome
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Pathway
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Disease
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