DPM1 (Human) Recombinant Protein (Q01)
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More Files
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Specification
Product Description
Human DPM1 partial ORF ( NP_003850, 161 a.a. - 260 a.a.) recombinant protein with GST-tag at N-terminal.
Sequence
RKIISRGANFLTQILLRPGASDLTGSFRLYRKEVLEKLIEKCVSKGYVFQMEMIVRARQLNYTIGEVPISFVDRVYGESKLGGNEIVSFLKGLLTLFATT
Host
Wheat Germ (in vitro)
Theoretical MW (kDa)
36.74
Interspecies Antigen Sequence
Mouse (91); Rat (91)
Preparation Method
Purification
Glutathione Sepharose 4 Fast Flow
Quality Control Testing
12.5% SDS-PAGE Stained with Coomassie Blue.
Storage Buffer
50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.
Storage Instruction
Store at -80°C. Aliquot to avoid repeated freezing and thawing.
Note
Best use within three months from the date of receipt of this protein.
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Applications
Enzyme-linked Immunoabsorbent Assay
Western Blot (Recombinant protein)
Antibody Production
Protein Array
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Gene Info — DPM1
Entrez GeneID
8813GeneBank Accession#
NM_003859Protein Accession#
NP_003850Gene Name
DPM1
Gene Alias
CDGIE, MPDS
Gene Description
dolichyl-phosphate mannosyltransferase polypeptide 1, catalytic subunit
Gene Ontology
HyperlinkGene Summary
Dolichol-phosphate mannose (Dol-P-Man) serves as a donor of mannosyl residues on the lumenal side of the endoplasmic reticulum (ER). Lack of Dol-P-Man results in defective surface expression of GPI-anchored proteins. Dol-P-Man is synthesized from GDP-mannose and dolichol-phosphate on the cytosolic side of the ER by the enzyme dolichyl-phosphate mannosyltransferase. Human DPM1 lacks a carboxy-terminal transmembrane domain and signal sequence and is regulated by DPM2. [provided by RefSeq
Other Designations
OTTHUMP00000031285|dolichol monophosphate mannose synthase|dolichyl-phosphate mannosyltransferase polypeptide 1
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Interactome
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Pathway
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Disease
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