IL18RAP rabbit monoclonal antibody
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Specification
Product Description
Rabbit monoclonal antibody raised against a human IL18RAP peptide using ARM Technology.
Immunogen
A synthetic peptide of human IL18RAP is used for rabbit immunization.
Customer or Abnova will decide on the preferred peptide sequence.Host
Rabbit
Library Construction
Non-fusion antibody library from rabbit spleen (ARM Technology).
Expression
Overexpression vector and transfection into 293H cell line.
Reactivity
Human
Purification
Protein A
Isotype
IgG
Quality Control Testing
Antibody reactive against human IL18RAP peptide by ELISA and mammalian transfected lysate by Western Blot.
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
Deliverable
Up to three rabbit IgG clones of 100 ug each will be delivered to customer.
Note
1. Customer may provide cell or tissue lysate for antibody screening.
2. Rabbit monoclonal antibody generated by ARM technology is amenable to antibody engineering including F(ab)2, IgG, scFv and different Fc and non-Fc conjugates per customer request. -
Applications
Western Blot (Transfected lysate)
ELISA
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Gene Info — IL18RAP
Entrez GeneID
8807GeneBank Accession#
IL18RAPGene Name
IL18RAP
Gene Alias
ACPL, CD218b, CDw218b, IL18RB, MGC120589, MGC120590
Gene Description
interleukin 18 receptor accessory protein
Omim ID
604509Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene is an accessory subunit of the heterodimeric receptor for IL18. This protein enhances the IL18 binding activity of IL18R1 (IL1RRP), a ligand binding subunit of IL18 receptor. The coexpression of IL18R1 and this protein is required for the activation of NF-kappaB and MAPK8 (JNK) in response to IL18. [provided by RefSeq
Other Designations
IL-18 receptor beta|OTTHUMP00000161337|accessory protein-like
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