CDC14A purified MaxPab mouse polyclonal antibody (B02P)
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More Files
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Western Blot (Transfected lysate)
Western Blot analysis of CDC14A expression in transfected 293T cell line (H00008556-T03) by CDC14A MaxPab polyclonal antibody.
Lane 1: CDC14A transfected lysate(66.60 KDa).
Lane 2: Non-transfected lysate.
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Specification
Product Description
Mouse polyclonal antibody raised against a full-length human CDC14A protein.
Immunogen
CDC14A (NP_003663.2, 1 a.a. ~ 594 a.a) full-length human protein.
Sequence
MAAESGELIGACEFMKDRLYFATLRNRPKSTVNTHYFSIDEELVYENFYADFGPLNLAMVYRYCCKLNKKLKSYSLSRKKIVHYTCFDQRKRANAAFLIGAYAVIYLKKTPEEAYRALLSGSNPPYLPFRDASFGNCTYNLTILDCLQGIRKGLQHGFFDFETFDVDEYEHYERVENGDFNWIVPGKFLAFSGPHPKSKIENGYPLHAPEAYFPYFKKHNVTAVVRLNKKIYEAKRFTDAGFEHYDLFFIDGSTPSDNIVRRFLNICENTEGAIAVHCKAGLGRTGTLIACYVMKHYRFTHAEIIAWIRICRPGSIIGPQQHFLEEKQASLWVQGDIFRSKLKNRPSSEGSINKILSGLDDMSIGGNLSKTQNMERFGEDNLEDDDVEMKNGITQGDKLRALKSQRQPRTSPSCAFRSDDTKGHPRAVSQPFRLSSSLQGSAVTLKTSKMALSPSATAKRINRTSLSSGATVRSFSINSRLASSLGNLNAATDDPENKKTSSSSKAGFTASPFTNLLNGSSQPTTRNYPELNNNQYNRSSNSNGGNLNSPPGPHSAKTEEHTTILRPSYTGLSSSSARFLSRSIPSLQSEYVHY
Host
Mouse
Reactivity
Human
Interspecies Antigen Sequence
Mouse (87); Rat (87)
Quality Control Testing
Antibody reactive against mammalian transfected lysate.
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Transfected lysate)
Western Blot analysis of CDC14A expression in transfected 293T cell line (H00008556-T03) by CDC14A MaxPab polyclonal antibody.
Lane 1: CDC14A transfected lysate(66.60 KDa).
Lane 2: Non-transfected lysate.
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Gene Info — CDC14A
Entrez GeneID
8556GeneBank Accession#
NM_003672Protein Accession#
NP_003663.2Gene Name
CDC14A
Gene Alias
cdc14, hCDC14
Gene Description
CDC14 cell division cycle 14 homolog A (S. cerevisiae)
Omim ID
603504Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene is a member of the dual specificity protein tyrosine phosphatase family. It is highly similar to Saccharomyces cerevisiae Cdc14, a protein tyrosine phosphatase involved in the exit of cell mitosis and initiation of DNA replication, suggesting a role in cell cycle control. This protein has been shown to interact with, and dephosphorylate tumor suppressor protein p53, and is thought to regulate the function of p53. Alternative splicing of this gene results in several transcript variants encoding distinct isoforms. [provided by RefSeq
Other Designations
CDC10 (cell division cycle 10, S. cerevisiae, homolog)|CDC14 homolog A|OTTHUMP00000012653|OTTHUMP00000012654|OTTHUMP00000012655|dual specificity protein phosphatase CDC14A
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Interactome
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Pathway
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Disease
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