DUSP11 293T Cell Transient Overexpression Lysate(Denatured)
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More Files
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SDS-PAGE Gel
DUSP11 transfected lysate.
Western Blot
Lane 1: DUSP11 transfected lysate ( 36.41 KDa)
Lane 2: Non-transfected lysate.
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Specification
Transfected Cell Line
293T
Plasmid
pCMV-DUSP11 full-length
Host
Human
Theoretical MW (kDa)
36.41
Interspecies Antigen Sequence
Mouse (69); Rat (68)
Quality Control Testing
Transient overexpression cell lysate was tested with Anti-DUSP11 antibody (H00008446-B01) by Western Blots.
SDS-PAGE Gel
DUSP11 transfected lysate.
Western Blot
Lane 1: DUSP11 transfected lysate ( 36.41 KDa)
Lane 2: Non-transfected lysate.Storage Buffer
1X Sample Buffer (50 mM Tris-HCl, 2% SDS, 10% glycerol, 300 mM 2-mercaptoethanol, 0.01% Bromophenol blue)
Storage Instruction
Store at -80°C. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot
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Gene Info — DUSP11
Entrez GeneID
8446GeneBank Accession#
NM_003584.1Protein Accession#
NP_003575.1Gene Name
DUSP11
Gene Alias
PIR1
Gene Description
dual specificity phosphatase 11 (RNA/RNP complex 1-interacting)
Omim ID
603092Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene is a member of the dual specificity protein phosphatase subfamily. These phosphatases inactivate their target kinases by dephosphorylating both the phosphoserine/threonine and phosphotyrosine residues. They negatively regulate members of the mitogen-activated protein (MAP) kinase superfamily (MAPK/ERK, SAPK/JNK, p38), which is associated with cellular proliferation and differentiation. Different members of the family of dual specificity phosphatases show distinct substrate specificities for various MAP kinases, different tissue distribution and subcellular localization, and different modes of inducibility of their expression by extracellular stimuli. This gene product is localized to the nucleus and binds directly to RNA and splicing factors, and thus it is suggested to participate in nuclear mRNA metabolism. [provided by RefSeq
Other Designations
RNA/RNP complex-interacting phosphatase|dual specificity phosphatase 11|serine/threonine specific protein phosphatase
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