PLA2G6 rabbit monoclonal antibody
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Specification
Product Description
Rabbit monoclonal antibody raised against a human PLA2G6 peptide using ARM Technology.
Immunogen
A synthetic peptide of human PLA2G6 is used for rabbit immunization.
Customer or Abnova will decide on the preferred peptide sequence.Host
Rabbit
Library Construction
Non-fusion antibody library from rabbit spleen (ARM Technology).
Expression
Overexpression vector and transfection into 293H cell line.
Reactivity
Human
Purification
Protein A
Isotype
IgG
Quality Control Testing
Antibody reactive against human PLA2G6 peptide by ELISA and mammalian transfected lysate by Western Blot.
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
Deliverable
Up to three rabbit IgG clones of 100 ug each will be delivered to customer.
Note
1. Customer may provide cell or tissue lysate for antibody screening.
2. Rabbit monoclonal antibody generated by ARM technology is amenable to antibody engineering including F(ab)2, IgG, scFv and different Fc and non-Fc conjugates per customer request. -
Applications
Western Blot (Transfected lysate)
ELISA
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Gene Info — PLA2G6
Entrez GeneID
8398GeneBank Accession#
PLA2G6Gene Name
PLA2G6
Gene Alias
CaI-PLA2, GVI, INAD1, IPLA2-VIA, PARK14, PLA2, PNPLA9, iPLA2
Gene Description
phospholipase A2, group VI (cytosolic, calcium-independent)
Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene is an A2 phospholipase, a class of enzyme that catalyzes the release of fatty acids from phospholipids. The encoded protein may play a role in phospholipid remodelling, arachidonic acid release, leukotriene and prostaglandin synthesis, fas-mediated apoptosis, and transmembrane ion flux in glucose-stimulated B-cells. Several transcript variants encoding multiple isoforms have been described, but the full-length nature of only two of them have been determined to date. [provided by RefSeq
Other Designations
OTTHUMP00000028877|calcium-independent phospholipase A2|cytosolic, calcium-independent phospholipase A2|patatin-like phospholipase domain containing 9|phospholipase A2, group VI
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