BAP1 (Human) Recombinant Protein (P01)
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More Files
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Specification
Product Description
Human BAP1 full-length ORF ( NP_004647.1, 1 a.a. - 729 a.a.) recombinant protein with GST-tag at N-terminal.
Sequence
MNKGWLELESDPGLFTLLVEDFGVKGVQVEEIYDLQSKCQGPVYGFIFLFKWIEERRSRRKVSTLVDDTSVIDDDIVNNMFFAHQLIPNSCATHALLSVLLNCSSVDLGPTLSRMKDFTKGFSPESKGYAIGNAPELAKAHNSHARPEPRHLPEKQNGLSAVRTMEAFHFVSYVPITGRLFELDGLKVYPIDHGPWGEDEEWTDKARRVIMERIGLATAGEPYHDIRFNLMAVVPDRRIKYEARLHVLKVNRQTVLEALQQLIRVTQPELIQTHKSQESQLPEESKSASNKSPLVLEANRAPAASEGNHTDGAEEAAGSCAQAPSHSPPNKPKLVVKPPGSSLNGVHPNPTPIVQRLPAFLDNHNYAKSPMQEEEDLAAGVGRSRVPVRPPQQYSDDEDDYEDDEEDDVQNTNSALRYKGKGTGKPGALSGSADGQLSVLQPNTINVLAEKLKESQKDLSIPLSIKTSSGAGSPAVAVPTHSQPSPTPSNESTDTASEIGSAFNSPLRSPIRSANPTRPSSPVTSHISKVLFGEDDSLLRVDCIRYNRAVRDLGPVISTGLLHLAEDGVLSPLALTEGGKGSSPSIRPIQGSQGSSSPVEKEVVEATDSREKTGMVRPGEPLSGEKYSPKELLALLKCVEAEIANYEACLKEEVEKRKKFKIDDQRRTHNYDEFICTFISMLAQEGMLANLVEQNISVRRRQGVSIGRLHKQRKPDRRKRSRPYKAKRQ
Host
Wheat Germ (in vitro)
Theoretical MW (kDa)
106.8
Interspecies Antigen Sequence
Mouse (93); Rat (92)
Preparation Method
Purification
Glutathione Sepharose 4 Fast Flow
Quality Control Testing
12.5% SDS-PAGE Stained with Coomassie Blue.
Storage Buffer
50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.
Storage Instruction
Store at -80°C. Aliquot to avoid repeated freezing and thawing.
Note
Best use within three months from the date of receipt of this protein.
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Applications
Enzyme-linked Immunoabsorbent Assay
Western Blot (Recombinant protein)
Antibody Production
Protein Array
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Gene Info — BAP1
Entrez GeneID
8314GeneBank Accession#
NM_004656.2Protein Accession#
NP_004647.1Gene Name
BAP1
Gene Alias
DKFZp686N04275, FLJ35406, FLJ37180, HUCEP-13, KIAA0272, UCHL2, hucep-6
Gene Description
BRCA1 associated protein-1 (ubiquitin carboxy-terminal hydrolase)
Omim ID
603089Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene localizes to the nucleus and it interacts with the RING finger domain of the breast cancer 1, early onset protein (BRCA1). This gene is thought to be a tumor suppressor gene that functions in the BRCA1 growth control pathway. There are multiple polyadenylation sites found in this gene. [provided by RefSeq
Other Designations
BRCA1 associated protein-1|cerebral protein-13|cerebral protein-6|ubiquitin carboxy-terminal hydrolase
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Interactome
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Disease
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Publication Reference
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Calpastatin participates in the regulation of cell migration in BAP1-deficient uveal melanoma cells.
Yue H, Meng FX, Qian J, Xu BB, Li G, Wu JH.
International Journal of Ophthalmology 2019 Nov; 12(11):1680.
Application:Array, Func, Recombinant protein.
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Calpastatin participates in the regulation of cell migration in BAP1-deficient uveal melanoma cells.
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