SYN3 293T Cell Transient Overexpression Lysate(Denatured)
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More Files
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SDS-PAGE Gel
SYN3 transfected lysate.
Western Blot
Lane 1: SYN3 transfected lysate ( 63.3 KDa)
Lane 2: Non-transfected lysate.
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Specification
Transfected Cell Line
293T
Plasmid
pCMV-SYN3 full-length
Host
Human
Theoretical MW (kDa)
63.3
Interspecies Antigen Sequence
Mouse (92); Rat (92)
Quality Control Testing
Transient overexpression cell lysate was tested with Anti-SYN3 antibody (H00008224-B01) by Western Blots.
SDS-PAGE Gel
SYN3 transfected lysate.
Western Blot
Lane 1: SYN3 transfected lysate ( 63.3 KDa)
Lane 2: Non-transfected lysate.Storage Buffer
1X Sample Buffer (50 mM Tris-HCl, 2% SDS, 10% glycerol, 300 mM 2-mercaptoethanol, 0.01% Bromophenol blue)
Storage Instruction
Store at -80°C. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot
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Gene Info — SYN3
Entrez GeneID
8224GeneBank Accession#
BC075065Protein Accession#
AAH75065Gene Name
SYN3
Gene Alias
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Gene Description
synapsin III
Omim ID
602705Gene Ontology
HyperlinkGene Summary
This gene is a member of the synapsin gene family. Synapsins encode neuronal phosphoproteins which associate with the cytoplasmic surface of synaptic vesicles. Family members are characterized by common protein domains, and they are implicated in synaptogenesis and the modulation of neurotransmitter release, suggesting a potential role in several neuropsychiatric diseases. The protein encoded by this gene shares the synapsin family domain model, with domains A, C, and E exhibiting the highest degree of conservation. The protein contains a unique domain J, located between domains C and E. Based on this gene's localization to 22q12.3, a possible schizophrenia susceptibility locus, and the established neurobiological roles of the synapsins, this family member may represent a candidate gene for schizophrenia. The TIMP3 gene is located within an intron of this gene and is transcribed in the opposite direction. Alternative splicing of this gene results in multiple splice variants that encode different isoforms. [provided by RefSeq
Other Designations
OTTHUMP00000028987|cN28H9.2 (synapsin III)
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Interactome
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Disease
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