SYN3 (Human) IP-WB Antibody Pair
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Specification
Product Description
This IP-WB antibody pair set comes with one antibody for immunoprecipitation and another to detect the precipitated protein in western blot.
Reactivity
Human
Interspecies Antigen Sequence
Mouse (92); Rat (92)
Quality Control Testing
Immunoprecipitation-Western Blot (IP-WB)
Immunoprecipitation of SYN3 transfected lysate using rabbit polyclonal anti-SYN3 and Protein A Magnetic Bead (U0007), and immunoblotted with mouse purified polyclonal anti-SYN3.
Supplied Product
Antibody pair set content:
1. Antibody pair for IP: rabbit polyclonal anti-SYN3 (300 ul)
2. Antibody pair for WB: mouse purified polyclonal anti-SYN3 (50 ug)
Storage Instruction
Store reagents of the antibody pair set at -20°C or lower. Please aliquot to avoid repeated freeze thaw cycle. Reagents should be returned to -20°C storage immediately after use.
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Applications
Immunoprecipitation-Western Blot
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Gene Info — SYN3
Entrez GeneID
8224Gene Name
SYN3
Gene Alias
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Gene Description
synapsin III
Omim ID
602705Gene Ontology
HyperlinkGene Summary
This gene is a member of the synapsin gene family. Synapsins encode neuronal phosphoproteins which associate with the cytoplasmic surface of synaptic vesicles. Family members are characterized by common protein domains, and they are implicated in synaptogenesis and the modulation of neurotransmitter release, suggesting a potential role in several neuropsychiatric diseases. The protein encoded by this gene shares the synapsin family domain model, with domains A, C, and E exhibiting the highest degree of conservation. The protein contains a unique domain J, located between domains C and E. Based on this gene's localization to 22q12.3, a possible schizophrenia susceptibility locus, and the established neurobiological roles of the synapsins, this family member may represent a candidate gene for schizophrenia. The TIMP3 gene is located within an intron of this gene and is transcribed in the opposite direction. Alternative splicing of this gene results in multiple splice variants that encode different isoforms. [provided by RefSeq
Other Designations
OTTHUMP00000028987|cN28H9.2 (synapsin III)
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Interactome
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Disease
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