MTERF monoclonal antibody (M01), clone 1A3
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Specification
Product Description
Mouse monoclonal antibody raised against a partial recombinant MTERF.
Immunogen
MTERF (NP_008911, 1 a.a. ~ 100 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Sequence
MQSLSLGQTSISKGLNYLTIMAPGNLWHMRNNFLFGSRCWMTRFSAENIFKSVSFRLFGVKCHNTDSEPLKNEDLLKNLLTMGVDIDMARKRQPGVFHRM
Host
Mouse
Reactivity
Human
Interspecies Antigen Sequence
Mouse (60)
Isotype
IgG2b Kappa
Quality Control Testing
Antibody Reactive Against Recombinant Protein.
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
ELISA
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Gene Info — MTERF
Entrez GeneID
7978GeneBank Accession#
NM_006980Protein Accession#
NP_008911Gene Name
MTERF
Gene Alias
MGC131634
Gene Description
mitochondrial transcription termination factor
Omim ID
602318Gene Ontology
HyperlinkGene Summary
This gene encodes a mitochondrial transcription termination factor. This protein participates in attenuating transcription from the mitochondrial genome; this attenuation allows higher levels of expression of 16S ribosomal RNA relative to the tRNA gene downstream. The product of this gene has three leucine zipper motifs bracketed by two basic domains that are all required for DNA binding. There is evidence that, for this protein, the zippers participate in intramolecular interactions that establish the three-dimensional structure required for DNA binding. [provided by RefSeq
Other Designations
transcription termination factor, mitochondrial
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Interactome
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Disease
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