MAPKAPK3 (Human) IP-WB Antibody Pair
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More Files
- More Functions
Immunoprecipitation of MAPKAPK3 transfected lysate using mouse monoclonal anti-MAPKAPK3 and Protein A Magnetic Bead (U0007), and immunoblotted with mouse monoclonal anti-MAPKAPK3.
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Specification
Product Description
This IP-WB antibody pair set comes with one antibody for immunoprecipitation and another to detect the precipitated protein in western blot.
Reactivity
Human
Interspecies Antigen Sequence
Mouse (94); Rat (93)
Quality Control Testing
Immunoprecipitation-Western Blot (IP-WB)
Immunoprecipitation of MAPKAPK3 transfected lysate using mouse monoclonal anti-MAPKAPK3 and Protein A Magnetic Bead (U0007), and immunoblotted with mouse monoclonal anti-MAPKAPK3.
Supplied Product
Antibody pair set content:
1. Antibody pair for IP: mouse monoclonal anti-MAPKAPK3 (300 ug)
2. Antibody pair for WB: mouse monoclonal anti-MAPKAPK3 (50 ug)
Storage Instruction
Store reagents of the antibody pair set at -20°C or lower. Please aliquot to avoid repeated freeze thaw cycle. Reagents should be returned to -20°C storage immediately after use.
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Applications
Immunoprecipitation-Western Blot
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Gene Info — MAPKAPK3
Entrez GeneID
7867Gene Name
MAPKAPK3
Gene Alias
3PK, MAPKAP3
Gene Description
mitogen-activated protein kinase-activated protein kinase 3
Omim ID
602130Gene Ontology
HyperlinkGene Summary
This gene encodes a member of the Ser/Thr protein kinase family. This kinase functions as a mitogen-activated protein kinase (MAP kinase)- activated protein kinase. MAP kinases are also known as extracellular signal-regulated kinases (ERKs), act as an integration point for multiple biochemical signals. This kinase was shown to be activated by growth inducers and stress stimulation of cells. In vitro studies demonstrated that ERK, p38 MAP kinase and Jun N-terminal kinase were all able to phosphorylate and activate this kinase, which suggested the role of this kinase as an integrative element of signaling in both mitogen and stress responses. This kinase was reported to interact with, phosphorylate and repress the activity of E47, which is a basic helix-loop-helix transcription factor known to be involved in the regulation of tissue-specific gene expression and cell differentiation. [provided by RefSeq
Other Designations
MAPKAP kinase 3
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Interactome
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Pathway
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Disease
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