XRCC4 (Human) IP-WB Antibody Pair
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Specification
Product Description
This IP-WB antibody pair set comes with one antibody for immunoprecipitation and another to detect the precipitated protein in western blot.
Reactivity
Human
Interspecies Antigen Sequence
Mouse (74); Rat (70)
Quality Control Testing
Immunoprecipitation-Western Blot (IP-WB)
Immunoprecipitation of XRCC4 transfected lysate using rabbit polyclonal anti-XRCC4 and Protein A Magnetic Bead (U0007), and immunoblotted with mouse polyclonal anti-XRCC4.
Supplied Product
Antibody pair set content:
1. Antibody pair for IP: rabbit polyclonal anti-XRCC4 (300 ul)
2. Antibody pair for WB: mouse polyclonal anti-XRCC4 (50 ul)
Storage Instruction
Store reagents of the antibody pair set at -20°C or lower. Please aliquot to avoid repeated freeze thaw cycle. Reagents should be returned to -20°C storage immediately after use.
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Applications
Immunoprecipitation-Western Blot
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Gene Info — XRCC4
Entrez GeneID
7518Gene Name
XRCC4
Gene Alias
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Gene Description
X-ray repair complementing defective repair in Chinese hamster cells 4
Omim ID
194363Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene functions together with DNA ligase IV and the DNA-dependent protein kinase in the repair of DNA double-strand break by non-homologous end joining and the completion of V(D)J recombination events. The non-homologous end-joining pathway is required both for normal development and for suppression of tumors. This gene functionally complements XR-1 Chinese hamster ovary cell mutant, which is impaired in DNA double-strand breaks produced by ionizing radiation and restriction enzymes. Alternative transcription initiation and alternative splicing generates several transcript variants. [provided by RefSeq
Other Designations
DNA repair protein XRCC4|X-ray repair cross complementing protein 4|X-ray repair, complementing defective, repair in Chinese hamster
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Interactome
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Pathway
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Disease
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