XRCC1 293T Cell Transient Overexpression Lysate(Denatured)
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More Files
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Specification
Transfected Cell Line
293T
Plasmid
pCMV-XRCC1 full-length
Host
Human
Theoretical MW (kDa)
69.5
Interspecies Antigen Sequence
Mouse (86)
Quality Control Testing
Transient overexpression cell lysate was tested with Anti-XRCC1 antibody (H00007515-B01) by Western Blots.
SDS-PAGE Gel
XRCC1 transfected lysate.
Western Blot
Lane 1: XRCC1 transfected lysate ( 69.5 KDa)
Lane 2: Non-transfected lysate.Storage Buffer
1X Sample Buffer (50 mM Tris-HCl, 2% SDS, 10% glycerol, 300 mM 2-mercaptoethanol, 0.01% Bromophenol blue)
Storage Instruction
Store at -80°C. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot
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Gene Info — XRCC1
Entrez GeneID
7515GeneBank Accession#
BC023593.2Protein Accession#
-Gene Name
XRCC1
Gene Alias
RCC
Gene Description
X-ray repair complementing defective repair in Chinese hamster cells 1
Omim ID
194360Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene is involved in the efficient repair of DNA single-strand breaks formed by exposure to ionizing radiation and alkylating agents. This protein interacts with DNA ligase III, polymerase beta and poly (ADP-ribose) polymerase to participate in the base excision repair pathway. It may play a role in DNA processing during meiogenesis and recombination in germ cells. A rare microsatellite polymorphism in this gene is associated with cancer in patients of varying radiosensitivity. [provided by RefSeq
Other Designations
DNA repair protein XRCC1|X-ray repair cross complementing protein 1|X-ray-repair, complementing defective, repair in Chinese hamster
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Interactome
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Pathway
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Disease
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