WARS 293T Cell Transient Overexpression Lysate(Denatured)
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Specification
Transfected Cell Line
293T
Plasmid
pCMV-WARS full-length
Host
Human
Theoretical MW (kDa)
51.92
Interspecies Antigen Sequence
Mouse (90); Rat (89)
Quality Control Testing
Transient overexpression cell lysate was tested with Anti-WARS antibody (H00007453-B01) by Western Blots.
SDS-PAGE Gel
WARS transfected lysate.
Western Blot
Lane 1: WARS transfected lysate ( 51.92 KDa)
Lane 2: Non-transfected lysate.Storage Buffer
1X Sample Buffer (50 mM Tris-HCl, 2% SDS, 10% glycerol, 300 mM 2-mercaptoethanol, 0.01% Bromophenol blue)
Storage Instruction
Store at -80°C. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot
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Gene Info — WARS
Entrez GeneID
7453GeneBank Accession#
NM_004184Protein Accession#
NP_004175Gene Name
WARS
Gene Alias
GAMMA-2, IFI53, IFP53
Gene Description
tryptophanyl-tRNA synthetase
Omim ID
191050Gene Ontology
HyperlinkGene Summary
Aminoacyl-tRNA synthetases catalyze the aminoacylation of tRNA by their cognate amino acid. Because of their central role in linking amino acids with nucleotide triplets contained in tRNAs, aminoacyl-tRNA synthetases are thought to be among the first proteins that appeared in evolution. Two forms of tryptophanyl-tRNA synthetase exist, a cytoplasmic form, named WARS, and a mitochondrial form, named WARS2. Tryptophanyl-tRNA synthetase (WARS) catalyzes the aminoacylation of tRNA(trp) with tryptophan and is induced by interferon. Tryptophanyl-tRNA synthetase belongs to the class I tRNA synthetase family. Four transcript variants encoding two different isoforms have been found for this gene. [provided by RefSeq
Other Designations
interferon-induced protein 53|tryptophan tRNA ligase 1, cytoplasmic
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Interactome
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Pathway
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Disease
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