UROS rabbit monoclonal antibody
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Specification
Product Description
Rabbit monoclonal antibody raised against a human UROS peptide using ARM Technology.
Immunogen
A synthetic peptide of human UROS is used for rabbit immunization.
Customer or Abnova will decide on the preferred peptide sequence.Host
Rabbit
Library Construction
Non-fusion antibody library from rabbit spleen (ARM Technology).
Expression
Overexpression vector and transfection into 293H cell line.
Reactivity
Human
Purification
Protein A
Isotype
IgG
Quality Control Testing
Antibody reactive against human UROS peptide by ELISA and mammalian transfected lysate by Western Blot.
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
Deliverable
Up to three rabbit IgG clones of 100 ug each will be delivered to customer.
Note
1. Customer may provide cell or tissue lysate for antibody screening.
2. Rabbit monoclonal antibody generated by ARM technology is amenable to antibody engineering including F(ab)2, IgG, scFv and different Fc and non-Fc conjugates per customer request. -
Applications
Western Blot (Transfected lysate)
ELISA
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Gene Info — UROS
Entrez GeneID
7390GeneBank Accession#
UROSGene Name
UROS
Gene Alias
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Gene Description
uroporphyrinogen III synthase
Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene catalyzes the fourth step of porphyrin biosynthesis in the heme biosynthetic pathway. Defects in this gene cause congenital erythropoietic porphyria (Gunther's disease). [provided by RefSeq
Other Designations
OTTHUMP00000020709|OTTHUMP00000020710|congenital erythropoietic porphyria
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Interactome
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Pathway
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