UROD monoclonal antibody (M08), clone 2F5
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More Files
- More Functions
Sandwich ELISA (Recombinant protein)
Detection limit for recombinant GST tagged UROD is approximately 0.1ng/ml as a capture antibody.
Western Blot detection against Immunogen (36.74 KDa) .
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Specification
Product Description
Mouse monoclonal antibody raised against a partial recombinant UROD.
Immunogen
UROD (NP_000365, 268 a.a. ~ 367 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Sequence
ALEELAQAGYEVVGLDWTVAPKKARECVGKTVTLQGNLDPCALYASEEEIGQLVKQMLDDFGPHRYIANLGHGLYPDMDPEHVGAFVDAVHKHSRLLRQN
Host
Mouse
Reactivity
Human
Isotype
IgG1 Kappa
Quality Control Testing
Antibody Reactive Against Recombinant Protein.
Western Blot detection against Immunogen (36.74 KDa) .
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Recombinant protein)
Sandwich ELISA (Recombinant protein)
Detection limit for recombinant GST tagged UROD is approximately 0.1ng/ml as a capture antibody.ELISA
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Gene Info — UROD
Entrez GeneID
7389GeneBank Accession#
NM_000374Protein Accession#
NP_000365Gene Name
UROD
Gene Alias
PCT
Gene Description
uroporphyrinogen decarboxylase
Omim ID
176100Gene Ontology
HyperlinkGene Summary
This gene encodes the fifth enzyme of the heme biosynthetic pathway. This enzyme is responsible for catalyzing the conversion of uroporphyrinogen to coproporphyrinogen through the removal of four carboxymethyl side chains. Mutations and deficiency in this enzyme are known to cause familial porphyria cutanea tarda and hepatoerythropoetic porphyria. [provided by RefSeq
Other Designations
OTTHUMP00000010502|fifth enzyme of heme biosynthetic pathway|fifth enzyme of the heme biosynthetic pathway|uroporphyrinogen III decarboxylase
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Interactome
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Pathway
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Disease
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