UGDH DNAxPab
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Specification
Product Description
Rabbit polyclonal antibody raised against a partial-length human UGDH DNA using DNAx™ Immune technology.
Technology
Immunogen
Extracellular membrane domain (ECD) human DNA
Host
Rabbit
Reactivity
Human
Purification
Protein A
Quality Control Testing
Antibody reactive against mammalian transfected lysate.
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Transfected lysate)
Immunofluorescence (Transfected cell)
Flow Cytometry (Transfected cell)
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Gene Info — UGDH
Entrez GeneID
7358GeneBank Accession#
NM_003359.2Protein Accession#
NP_003350.1Gene Name
UGDH
Gene Alias
GDH, UDP-GlcDH, UDPGDH, UGD
Gene Description
UDP-glucose dehydrogenase
Omim ID
603370Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene converts UDP-glucose to UDP-glucuronate and thereby participates in the biosynthesis of glycosaminoglycans such as hyaluronan, chondroitin sulfate, and heparan sulfate. These glycosylated compounds are common components of the extracellular matrix and likely play roles in signal transduction, cell migration, and cancer growth and metastasis. The expression of this gene is up-regulated by transforming growth factor beta and down-regulated by hypoxia. [provided by RefSeq
Other Designations
UDP-glucose 6-dehydrogenase|uridine diphospho-glucose dehydrogenase
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Interactome
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Pathway
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Disease
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