UGCG (Human) Recombinant Protein (Q01)
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Specification
Product Description
Human UGCG partial ORF ( NP_003349, 33 a.a. - 131 a.a.) recombinant protein with GST-tag at N-terminal.
Sequence
TRLHLNKKATDKQPYSKLPGVSLLKPLKGVDPNLINNLETFFELDYPKYEVLLCVQDHDDPAIDVCKKLLGKYPNVDARLFIGGKKVGINPKINNLMPG
Host
Wheat Germ (in vitro)
Theoretical MW (kDa)
36.63
Interspecies Antigen Sequence
Mouse (99); Rat (98)
Preparation Method
Purification
Glutathione Sepharose 4 Fast Flow
Quality Control Testing
12.5% SDS-PAGE Stained with Coomassie Blue.
Storage Buffer
50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.
Storage Instruction
Store at -80°C. Aliquot to avoid repeated freezing and thawing.
Note
Best use within three months from the date of receipt of this protein.
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Applications
Enzyme-linked Immunoabsorbent Assay
Western Blot (Recombinant protein)
Antibody Production
Protein Array
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Gene Info — UGCG
Entrez GeneID
7357GeneBank Accession#
NM_003358Protein Accession#
NP_003349Gene Name
UGCG
Gene Alias
GCS
Gene Description
UDP-glucose ceramide glucosyltransferase
Omim ID
602874Gene Ontology
HyperlinkGene Summary
Glycosphingolipids (GSLs) are a group of membrane components that contain lipid and sugar moieties. They are present in essentially all animal cells and are believed to have important roles in various cellular processes. UDP-glucose ceramide glucosyltransferase catalyzes the first glycosylation step in glycosphingolipid biosynthesis. The product, glucosylceramide, is the core structure of more than 300 GSLs. UGCG is widely expressed and transciption is upregulated during keratinocyte differentiation. [provided by RefSeq
Other Designations
OTTHUMP00000021925|ceramide glucosyltransferase|glucosylceramide synthase
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Interactome
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Disease
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