NR2C1 rabbit monoclonal antibody
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Specification
Product Description
Rabbit monoclonal antibody raised against a human NR2C1 peptide using ARM Technology.
Immunogen
A synthetic peptide of human NR2C1 is used for rabbit immunization.
Customer or Abnova will decide on the preferred peptide sequence.Host
Rabbit
Library Construction
Non-fusion antibody library from rabbit spleen (ARM Technology).
Expression
Overexpression vector and transfection into 293H cell line.
Reactivity
Human
Purification
Protein A
Isotype
IgG
Quality Control Testing
Antibody reactive against human NR2C1 peptide by ELISA and mammalian transfected lysate by Western Blot.
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
Deliverable
Up to three rabbit IgG clones of 100 ug each will be delivered to customer.
Note
1. Customer may provide cell or tissue lysate for antibody screening.
2. Rabbit monoclonal antibody generated by ARM technology is amenable to antibody engineering including F(ab)2, IgG, scFv and different Fc and non-Fc conjugates per customer request. -
Applications
Western Blot (Transfected lysate)
ELISA
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Gene Info — NR2C1
Entrez GeneID
7181GeneBank Accession#
NR2C1Gene Name
NR2C1
Gene Alias
TR2
Gene Description
nuclear receptor subfamily 2, group C, member 1
Omim ID
601529Gene Ontology
HyperlinkGene Summary
This gene encodes a nuclear hormone receptor characterized by a highly conserved DNA binding domain (DBD), a variable hinge region, and a carboxy-terminal ligand binding domain (LBD) that is typical for all members of the steroid/thyroid hormone receptor superfamily. This protein also belongs to a large family of ligand-inducible transcription factors that regulate gene expression by binding to specific DNA sequences within promoters of target genes. Multiple alternatively spliced transcript variants have been described, but the full-length nature of some of these variants has not been determined. [provided by RefSeq
Other Designations
TR2 nuclear hormone receptor|nuclear receptor subfamily 2, group C isoform|orphan nuclear receptor TR2|testicular receptor 2
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Interactome
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Disease
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