TMPRSS2 293T Cell Transient Overexpression Lysate(Denatured)
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More Files
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SDS-PAGE Gel
TMPRSS2 transfected lysate.
Western Blot
Lane 1: TMPRSS2 transfected lysate ( 53.9 KDa)
Lane 2: Non-transfected lysate.
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Specification
Transfected Cell Line
293T
Plasmid
pCMV-TMPRSS2 full-length
Host
Human
Theoretical MW (kDa)
53.9
Interspecies Antigen Sequence
Mouse (78); Rat (78)
Quality Control Testing
Transient overexpression cell lysate was tested with Anti-TMPRSS2antibody (H00007113-B01P)byWesternBlots.
SDS-PAGE Gel
TMPRSS2 transfected lysate.
Western Blot
Lane 1: TMPRSS2 transfected lysate ( 53.9 KDa)
Lane 2: Non-transfected lysate.Storage Buffer
1X Sample Buffer (50 mM Tris-HCl, 2% SDS, 10% glycerol, 300 mM 2-mercaptoethanol, 0.01% Bromophenol blue)
Storage Instruction
Store at -80°C. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot
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Gene Info — TMPRSS2
Entrez GeneID
7113GeneBank Accession#
BC051839.1Protein Accession#
AAH51839.1Gene Name
TMPRSS2
Gene Alias
FLJ41954, PP9284, PRSS10
Gene Description
transmembrane protease, serine 2
Omim ID
602060Gene Ontology
HyperlinkGene Summary
This gene encodes a protein that belongs to the serine protease family. The encoded protein contains a type II transmembrane domain, a receptor class A domain, a scavenger receptor cysteine-rich domain and a protease domain. Serine proteases are known to be involved in many physiological and pathological processes. This gene was demonstrated to be up-regulated by androgenic hormones in prostate cancer cells and down-regulated in androgen-independent prostate cancer tissue. The protease domain of this protein is thought to be cleaved and secreted into cell media after autocleavage. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq
Other Designations
epitheliasin
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Interactome
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Disease
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