ICAM5 (Human) Recombinant Protein (Q01)
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More Files
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Specification
Product Description
Human ICAM5 partial ORF ( NP_003250.2, 34 a.a. - 131 a.a.) recombinant protein with GST-tag at N-terminal.
Sequence
FWADLQPRVAFVERGGSLWLNCSTNCPRPERGGLETSLRRNGTQRGLRWLARQLVDIREPETQPVCFFRCARRTLQARGLIRTFQRPDRVELMPLPPW
Host
Wheat Germ (in vitro)
Theoretical MW (kDa)
36.52
Interspecies Antigen Sequence
Mouse (97); Rat (98)
Preparation Method
Purification
Glutathione Sepharose 4 Fast Flow
Quality Control Testing
12.5% SDS-PAGE Stained with Coomassie Blue.
Storage Buffer
50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.
Storage Instruction
Store at -80°C. Aliquot to avoid repeated freezing and thawing.
Note
Best use within three months from the date of receipt of this protein.
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Applications
Enzyme-linked Immunoabsorbent Assay
Western Blot (Recombinant protein)
Antibody Production
Protein Array
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Gene Info — ICAM5
Entrez GeneID
7087GeneBank Accession#
NM_003259Protein Accession#
NP_003250.2Gene Name
ICAM5
Gene Alias
TLCN, TLN
Gene Description
intercellular adhesion molecule 5, telencephalin
Omim ID
601852Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene is a member of the intercellular adhesion molecule (ICAM) family. All ICAM proteins are type I transmembrane glycoproteins, contain 2-9 immunoglobulin-like C2-type domains, and bind to the leukocyte adhesion LFA-1 protein. This protein is expressed on the surface of telencephalic neurons and displays two types of adhesion activity, homophilic binding between neurons and heterophilic binding between neurons and leukocytes. It may be a critical component in neuron-microglial cell interactions in the course of normal development or as part of neurodegenerative diseases. [provided by RefSeq
Other Designations
intercellular adhesion molecule 5|telencephalin
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Interactome
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Disease
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