SOD3 monoclonal antibody (M01), clone 5C3
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More Files
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Specification
Product Description
Mouse monoclonal antibody raised against a partial recombinant SOD3.
Immunogen
SOD3 (AAH14418, 26 a.a. ~ 125 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Sequence
EPNSDSAEWIRDMYAKVTEIWQEVMQRRDDDGTLHAACQVQPSATLDAAQPRVTGVVLFRQLAPRAKLDAFFALEGFPTEPNSSSRAIHVHQFGDLSQGC
Host
Mouse
Reactivity
Human
Interspecies Antigen Sequence
Mouse (62); Rat (57)
Isotype
IgG2a Kappa
Quality Control Testing
Antibody Reactive Against Recombinant Protein.
Western Blot detection against Immunogen (36.41 KDa) .
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Recombinant protein)
Sandwich ELISA (Recombinant protein)
Detection limit for recombinant GST tagged SOD3 is approximately 10ng/ml as a capture antibody.ELISA
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Gene Info — SOD3
Entrez GeneID
6649GeneBank Accession#
BC014418Protein Accession#
AAH14418Gene Name
SOD3
Gene Alias
EC-SOD, MGC20077
Gene Description
superoxide dismutase 3, extracellular
Omim ID
185490Gene Ontology
HyperlinkGene Summary
This gene encodes a member of the superoxide dismutase (SOD) protein family. SODs are antioxidant enzymes that catalyze the dismutation of two superoxide radicals into hydrogen peroxide and oxygen. The product of this gene is thought to protect the brain, lungs, and other tissues from oxidative stress. The protein is secreted into the extracellular space and forms a glycosylated homotetramer that is anchored to the extracellular matrix (ECM) and cell surfaces through an interaction with heparan sulfate proteoglycan and collagen. A fraction of the protein is cleaved near the C-terminus before secretion to generate circulating tetramers that do not interact with the ECM. [provided by RefSeq
Other Designations
OTTHUMP00000158715
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Interactome
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Disease
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